Chromatography- High Performance Liquid Chromatography

Helen Gika, George Kaklamanos, Panagiotis Manesiotis, Georgios Theodoridis

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

2 Citations (Scopus)

Abstract

High-performance liquid chromatography (HPLC) is a major analytic tool in contemporary science, with possibly the highest number of systems installed and running globally. Modern HPLC offers high resolutions allowing the quantitative determination of target analytes within complex matrices by its compatibility with a number of detectors. The article describes the major technological characteristics of HPLC, reviewing separation mechanisms and their application in health and food science. Separation modes and media, key instrumental parameters, compatibility with detection modes, and applications are briefly discussed, aiming to provide helpful hints to the reader in the search for appropriate analytic techniques for a given task.
Original languageEnglish
Title of host publicationEncyclopedia of Food and Health
EditorsB Caballero, P Finglass, F Toldra
PublisherElsevier
Pages93-99
Number of pages7
ISBN (Electronic)9780123849533
ISBN (Print)9780123849472
DOIs
Publication statusPublished - 2016

Keywords

  • Affinity chromatography
  • Clinical analysis
  • Food analysis
  • High-performance liquid chromatography
  • HPLC
  • Ion exchange chromatography
  • Ion pair chromatography
  • LC-MS
  • Normal phase separations
  • Reverse phase separations
  • Superficially porous particles
  • UHPLC

ASJC Scopus subject areas

  • Analytical Chemistry

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