Circulating gastrointestinal hormones in patients with flatulent dyspepsia, with and without gallbladder disease

R G Watson, C Shaw, K D Buchanan, A H Love

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Abstract

Fasting and post-prandial circulating levels of insulin, gastrin, gastric inhibitory polypeptide, pancreatic polypeptide and neurotensin were measured in patients with flatulent dyspepsia, with and without gallbladder disease and post-cholecystectomy. Levels were also measured in non-dyspeptic patients with gallbladder disease and normal controls. There were no consistent significant differences from controls for fasting and post-prandial responses in patients with a history of dyspepsia or those who experienced dyspepsia at the time of the test. In patients with gallbladder disease, with and without dyspepsia, there was a reduced neurotensin response compared to normal controls. It is concluded that circulating levels of these hormones are not related to symptoms of flatulent dyspepsia.
Original languageEnglish
Pages (from-to)211-6
Number of pages6
JournalDigestion
Volume35
Issue number4
Publication statusPublished - 1986

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    Watson, R. G., Shaw, C., Buchanan, K. D., & Love, A. H. (1986). Circulating gastrointestinal hormones in patients with flatulent dyspepsia, with and without gallbladder disease. Digestion, 35(4), 211-6.