Clinical features of schizophrenia and linkage to chromosomes 5q, 6p, 8p, and 10p in the Irish Study of High-Density Schizophrenia Families

K S Kendler, J M Myers, F A O'Neill, R Martin, B Murphy, C J MacLean, D Walsh, R E Straub

Research output: Contribution to journalArticlepeer-review

98 Citations (Scopus)

Abstract

Schizophrenia is clinically heterogeneous. Recent linkage studies suggest that multiple genes are important in the etiology of schizophrenia. The authors examined the hypothesis of whether the clinical variability in schizophrenia is due to genetic heterogeneity.
Original languageEnglish
Pages (from-to)402-8
Number of pages7
JournalAmerican Journal of Psychiatry
Volume157
Issue number3
Publication statusPublished - Mar 2000

Keywords

  • Chromosomes, Human, Pair 10
  • Chromosomes, Human, Pair 5
  • Chromosomes, Human, Pair 6
  • Chromosomes, Human, Pair 8
  • Family
  • Genetic Heterogeneity
  • Genetic Linkage
  • Genetic Predisposition to Disease
  • Humans
  • Ireland
  • Lod Score
  • Models, Genetic
  • Northern Ireland
  • Schizophrenia

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