Clinical relevance of the ESKAPE pathogens.

Jack Pendleton, Sean Gorman, Brendan Gilmore

Research output: Contribution to journalArticle

458 Citations (Scopus)

Abstract

In recent years, the Infectious Diseases Society of America has highlighted a faction of antibiotic-resistant bacteria (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter spp.) - acronymically dubbed 'the ESKAPE pathogens' - capable of 'escaping' the biocidal action of antibiotics and mutually representing new paradigms in pathogenesis, transmission and resistance. This review aims to consolidate clinically relevant background information on the ESKAPE pathogens and provide a contemporary summary of bacterial resistance, alongside pertinent microbiological considerations necessary to face the mounting threat of antimicrobial resistance.
Original languageEnglish
Pages (from-to)297-308
JournalExpert review of anti-infective therapy
Volume11
Issue number3
DOIs
Publication statusPublished - Jan 2013

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Microbiology
  • Virology

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