Combining biomarker screening and mass-spectrometric analysis to detect hormone abuse in cattle

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39 Citations (Scopus)

Abstract

Since the introduction of the European ban on hormones in 1989, its implementation has proved to be an enormous challenge to regulatory authorities, because the great economic benefits that result from illegal misuse of growth promoters in animal production encourage their continued use. In efforts to challenge black-market trade in hormones, there have been many analytical advances. Recently, both effect-based bioanalysis for screening to target illegal misuse and improved mass-spectrometry-based confirmatory analysis have greatly increased the likelihood of detecting hormone abuse. This review outlines analytical methods currently used for detecting hormone abuse and presents advances in new approaches based on biological determinants that may complement these techniques in the future. (C) 2009 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)665-675
Number of pages11
JournalTRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume28
Issue number6
DOIs
Publication statusPublished - Jun 2009

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Environmental Chemistry

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