Combining cataract surgery with 25-gauge high-speed pars plana vitrectomy: A prospective study

Alfonso Savastano, Chiara Lenzetti*, Lucia Finocchio, Daniela Bacherini, Fabrizio Giansanti, Ruggero Tartaro, Valerio Piccirillo, Maria Cristina Savastano, Gianni Virgili, Stanislao Rizzo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Purpose: To compare visual outcome and postoperative complications of combined 25-gauge pars plana vitrectomy and phacoemulsification with vitrectomy alone surgery in patients with epiretinal membrane and macular hole. Methods: A total of 110 eyes (73 eyes with epiretinal membrane and 37 eyes with macular hole) were enrolled in this prospective study. The eyes were divided into two groups: Group A included 55 eyes which underwent phacovitrectomy at the same time and Group B included 55 eyes which underwent vitrectomy alone. Follow-up visits were at 1, 3, and 6 months. Results: The best-corrected visual acuity correlation by analysis of variance measurement showed statistically non-significant differences between the two groups (p = 0.32). The post hoc analysis from baseline, 1°, 2°, and 3° follow-ups was not statistically significant (p > 0.05). The most common postoperative complication was cystoid macular edema that has been detected in 11 patients (10%) (seven eyes in Group A and four eyes in Group B): 2 patients (1.8%) developed a chronic macular edema. Intraocular hypertension occurred in five eyes (4.5%) (three in Group A and two in Group B). Four eyes (3.6%) underwent another surgical procedure for a persistent macular hole (two in Group A and two in Group B). The intraocular lens repositioning was performed one day after surgery in three eyes (2.7%) (Group A). The mean preoperative visual acuity was not different between the two groups (p = 0.80). Conclusion: No significative differences between combined surgery and vitrectomy alone have been detected, in terms of postoperative complications and visual outcome.

Original languageEnglish
JournalEuropean Journal of Ophthalmology
Early online date23 Jan 2020
Publication statusEarly online date - 23 Jan 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2020.

Copyright 2020 Elsevier B.V., All rights reserved.


  • Epiretinal membrane
  • macular hole
  • pars plana vitrectomy
  • phacoemulsification
  • postoperative posterior segment/vitreous problems

ASJC Scopus subject areas

  • Ophthalmology


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