Comparative genomic insights into yersinia hibernica – a commonly misidentified yersinia enterocolitica-like organism

Scott Van Nguyen*, Dechamma Mundanda Muthappa, Athmanya K. Eshwar, James F. Buckley, Brenda P. Murphy, Roger Stephan, Angelika Lehner, Séamus Fanning

*Corresponding author for this work

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Abstract

Food-associated outbreaks linked to enteropathogenic Yersinia enterocolitica are of concern to public health. Pigs and their meat are recognized risk factors for transmission of Y. enterocolitica. This study aimed to describe the comparative genomics of Y. enterocolitica along with a number of misclassified Yersinia isolates, now constituting the recently described Yersinia hibernica. The latter was originally cultured from an environmental sample taken at a pig slaughterhouse. Unique features were identified in the genome of Y. hibernica, including a novel integrative conjugative element (ICE), denoted as ICEYh-1 contained within a 255 kbp region of plasticity. In addition, a zebrafish embryo infection model was adapted and applied to assess the virulence potential among Yersinia isolates including Y. hibernica.

Original languageEnglish
Number of pages10
JournalMicrobial Genomics
Volume6
Issue number9
DOIs
Publication statusPublished - 23 Jul 2020

Bibliographical note

Publisher Copyright:
© 2020 The Authors.

Keywords

  • Comparative genomics
  • Yersinia enterocolitica
  • Yersinia hibernica
  • Zebrafish embryo

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology
  • Molecular Biology
  • Genetics

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