Abstract
Food-associated outbreaks linked to enteropathogenic Yersinia enterocolitica are of concern to public health. Pigs and their meat are recognized risk factors for transmission of Y. enterocolitica. This study aimed to describe the comparative genomics of Y. enterocolitica along with a number of misclassified Yersinia isolates, now constituting the recently described Yersinia hibernica. The latter was originally cultured from an environmental sample taken at a pig slaughterhouse. Unique features were identified in the genome of Y. hibernica, including a novel integrative conjugative element (ICE), denoted as ICEYh-1 contained within a 255 kbp region of plasticity. In addition, a zebrafish embryo infection model was adapted and applied to assess the virulence potential among Yersinia isolates including Y. hibernica.
| Original language | English |
|---|---|
| Number of pages | 10 |
| Journal | Microbial Genomics |
| Volume | 6 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 23 Jul 2020 |
Bibliographical note
Publisher Copyright:© 2020 The Authors.
Keywords
- Comparative genomics
- Yersinia enterocolitica
- Yersinia hibernica
- Zebrafish embryo
ASJC Scopus subject areas
- Epidemiology
- Microbiology
- Molecular Biology
- Genetics
Access to Document
- Comparative genomic insights into Yersinia hibernica – a commonly misidentified Yersinia enterocolitica-like organism
Copyright 2020 the authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.