Comparison of two assays, a faecal egg count reduction test (FECRT) and a coproantigen reduction test (CRT), for the diagnosis of resistance to triclabendazole in Fasciola hepatica in sheep

Michelle Flanagan, D Edgar, A. Gordon, Ronnie Hanna, Gerard Brennan, Ian Fairweather

Research output: Contribution to journalArticlepeer-review

60 Citations (Scopus)

Abstract

A sheep trial was performed to evaluate two diagnostic assays, a faecal egg count reduction test (FECRT) and a coproantigen reduction test (CRT), for the diagnosis of resistance of Fasciola hepatica to triclabendazole (TCBZ). The FECRT defines successful TCBZ treatment as a 95% or greater reduction in fluke faecal egg counts (FECs) at 14 days post-treatment (dpt). The CRT defines effective TCBZ treatment as faeces negative for Fasciola coproantigens at 14 dpt, as measured by the commercial BIO K201 coproantigen ELISA (Bio-X Diagnostics, Jemelle, Belgium).
Original languageEnglish
Pages (from-to)170-176
Number of pages7
JournalVeterinary Parasitology
Volume176
Issue number2-3
DOIs
Publication statusPublished - 10 Mar 2011

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)

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