Projects per year
Abstract
A substantial proportion of aetiological risks for many cancers and chronic diseases remain unexplained. Using geochemical soil and stream water samples collected as part of the Tellus Project studies, current research is investigating naturally occurring background levels of potentially toxic elements (PTEs) in soils and stream sediments and their possible relationship with progressive chronic kidney disease (CKD). The Tellus geological mapping project, Geological Survey Northern Ireland, collected soil sediment and stream water samples on a grid of one sample site every 2 km2 across the rural areas of Northern Ireland resulting in an excess of 6800 soil sampling locations and more than 5800 locations for stream water sampling. Accumulation of several PTEs including arsenic, cadmium, chromium, lead and mercury have been linked with human health and implicated in renal function decline. The hypothesis is that long-term exposure will result in cumulative exposure to PTEs and act as risk factor(s) for cancer and diabetes related CKD and its progression. The ‘bioavailable’ fraction of total PTE soil concentration depends on the ‘bioaccessible’ proportion through an exposure pathway. Recent work has explored this bioaccessible fraction for a range of PTEs across Northern Ireland. In this study the compositional nature of the multivariate geochemical PTE variables and bioaccessible data is explored to augment the investigation into the potential relationship between PTEs, bioaccessibility and disease data.
Original language | English |
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Publication status | Published - 20 Oct 2014 |
Event | 16th Annual Conference of the International Association for Mathematical Geosciences - New Delhi, India Duration: 17 Oct 2014 → 20 Oct 2014 |
Conference
Conference | 16th Annual Conference of the International Association for Mathematical Geosciences |
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Country/Territory | India |
City | New Delhi |
Period | 17/10/2014 → 20/10/2014 |
Keywords
- geochemistry
- bioaccessibility
- compositional data analysis, log-ratios, mapping
ASJC Scopus subject areas
- General Environmental Science
- General Health Professions
Fingerprint
Dive into the research topics of 'Compositonal Analysis of Potentially harmful Elements in Soils: Implications for Epidemiology and Kidney Disease'. Together they form a unique fingerprint.Projects
- 1 Finished
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R3977GGY: Trace Element Abundance and Human Epidemiology - The Tellus Case Study<GEOG/PLANNING>
McKinley, J. (PI) & Ofterdinger, U. (CoI)
01/08/2007 → 30/06/2008
Project: Research
Research output
- 2 Article
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Comparison of methods used to calculate typical threshold values for potentially toxic elements in soil
McIlwaine, R., Cox, S., Doherty, R., Palmer, S., Ofterdinger, U. & McKinley, J. M., Oct 2014, In: Environmental Geochemistry and Health. 36, 5, p. 953-971Research output: Contribution to journal › Article › peer-review
Open AccessFile38 Citations (Scopus)1608 Downloads (Pure) -
Investigating local relationships between trace elements in soils and cancer data
McKinley, J. M., Ofterdinger, U., Young, M., Barsby, A. & Gavin, A., Aug 2013, In: Spatial Statistics. 5, p. 25-41 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)528 Downloads (Pure)