Concordant Association of Insulin Degrading Enzyme Gene (IDE) Variants with IDE mRNA, A beta, and Alzheimer's Disease

M.M. Carrasquillo; O. Belbin; F.G. Zou; M. Allen; N. Ertekin-Taner; M. Ansari; S.L. Wilcox; M.R. Kashino; L. Ma; L.H. Younkin; S.G. Younkin; C.S. Younkin; T.A. Dincman; M.E. Howard; C.C. Howell; C.M. Stanton; C.M. Watson; M. Crump; V. Vitart; C. Hayward; N.D. Hastie; I. Rudan; H. Campbell; O. Polasek; K. Brown; Peter Passmore; David Craig; Jean McGuinness; Stephen Todd; P.G. Kehoe; D.M. Mann; A.D. Smith; H. Beaumont; D. Warden; C. Holmes; R. Heun; H. Kolsch; N. Kalsheker; V.S. Pankratz; D.W. Dickson; N.R. Graff-Radford; R.C. Petersen; A.F. Wright; S.G. Younkin; K. Morgan

doi:10.1371/journal.pone.0008764

Concordant Association of Insulin Degrading Enzyme Gene (IDE) Variants with IDE mRNA, A beta, and Alzheimer's Disease

M.M. Carrasquillo, O. Belbin, F.G. Zou, M. Allen, N. Ertekin-Taner, M. Ansari, S.L. Wilcox, M.R. Kashino, L. Ma, L.H. Younkin, S.G. Younkin, C.S. Younkin, T.A. Dincman, M.E. Howard, C.C. Howell, C.M. Stanton, C.M. Watson, M. Crump, V. Vitart, C. HaywardN.D. Hastie, I. Rudan, H. Campbell, O. Polasek, K. Brown, Peter Passmore, David Craig, Jean McGuinness, Stephen Todd, P.G. Kehoe, D.M. Mann, A.D. Smith, H. Beaumont, D. Warden, C. Holmes, R. Heun, H. Kolsch, N. Kalsheker, V.S. Pankratz, D.W. Dickson, N.R. Graff-Radford, R.C. Petersen, A.F. Wright, S.G. Younkin, K. Morgan

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Background: The insulin-degrading enzyme gene (IDE) is a strong functional and positional candidate for late onset Alzheimer's disease (LOAD).

Original language	English
Article number	e8764
Pages (from-to)	e8764
Number of pages	1
Journal	PLoS ONE
Volume	5
Issue number	1
DOIs	https://doi.org/10.1371/journal.pone.0008764
Publication status	Published - 19 Jan 2010

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Biochemistry,Genetics and Molecular Biology
General Medicine

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Carrasquillo, M. M., Belbin, O., Zou, F. G., Allen, M., Ertekin-Taner, N., Ansari, M., Wilcox, S. L., Kashino, M. R., Ma, L., Younkin, L. H., Younkin, S. G., Younkin, C. S., Dincman, T. A., Howard, M. E., Howell, C. C., Stanton, C. M., Watson, C. M., Crump, M., Vitart, V., ... Morgan, K. (2010). Concordant Association of Insulin Degrading Enzyme Gene (IDE) Variants with IDE mRNA, A beta, and Alzheimer's Disease. PLoS ONE, 5(1), e8764. Article e8764. https://doi.org/10.1371/journal.pone.0008764

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abstract = "Background: The insulin-degrading enzyme gene (IDE) is a strong functional and positional candidate for late onset Alzheimer's disease (LOAD).",

author = "M.M. Carrasquillo and O. Belbin and F.G. Zou and M. Allen and N. Ertekin-Taner and M. Ansari and S.L. Wilcox and M.R. Kashino and L. Ma and L.H. Younkin and S.G. Younkin and C.S. Younkin and T.A. Dincman and M.E. Howard and C.C. Howell and C.M. Stanton and C.M. Watson and M. Crump and V. Vitart and C. Hayward and N.D. Hastie and I. Rudan and H. Campbell and O. Polasek and K. Brown and Peter Passmore and David Craig and Jean McGuinness and Stephen Todd and P.G. Kehoe and D.M. Mann and A.D. Smith and H. Beaumont and D. Warden and C. Holmes and R. Heun and H. Kolsch and N. Kalsheker and V.S. Pankratz and D.W. Dickson and N.R. Graff-Radford and R.C. Petersen and A.F. Wright and S.G. Younkin and K. Morgan",

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Carrasquillo, MM, Belbin, O, Zou, FG, Allen, M, Ertekin-Taner, N, Ansari, M, Wilcox, SL, Kashino, MR, Ma, L, Younkin, LH, Younkin, SG, Younkin, CS, Dincman, TA, Howard, ME, Howell, CC, Stanton, CM, Watson, CM, Crump, M, Vitart, V, Hayward, C, Hastie, ND, Rudan, I, Campbell, H, Polasek, O, Brown, K, Passmore, P, Craig, D, McGuinness, J, Todd, S, Kehoe, PG, Mann, DM, Smith, AD, Beaumont, H, Warden, D, Holmes, C, Heun, R, Kolsch, H, Kalsheker, N, Pankratz, VS, Dickson, DW, Graff-Radford, NR, Petersen, RC, Wright, AF, Younkin, SG & Morgan, K 2010, 'Concordant Association of Insulin Degrading Enzyme Gene (IDE) Variants with IDE mRNA, A beta, and Alzheimer's Disease', PLoS ONE, vol. 5, no. 1, e8764, pp. e8764. https://doi.org/10.1371/journal.pone.0008764

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AU - Belbin, O.

AU - Zou, F.G.

AU - Allen, M.

AU - Ertekin-Taner, N.

AU - Ansari, M.

AU - Wilcox, S.L.

AU - Kashino, M.R.

AU - Ma, L.

AU - Younkin, L.H.

AU - Younkin, S.G.

AU - Younkin, C.S.

AU - Dincman, T.A.

AU - Howard, M.E.

AU - Howell, C.C.

AU - Stanton, C.M.

AU - Watson, C.M.

AU - Crump, M.

AU - Vitart, V.

AU - Hayward, C.

AU - Hastie, N.D.

AU - Rudan, I.

AU - Campbell, H.

AU - Polasek, O.

AU - Brown, K.

AU - Passmore, Peter

AU - Craig, David

AU - McGuinness, Jean

AU - Todd, Stephen

AU - Kehoe, P.G.

AU - Mann, D.M.

AU - Smith, A.D.

AU - Beaumont, H.

AU - Warden, D.

AU - Holmes, C.

AU - Heun, R.

AU - Kolsch, H.

AU - Kalsheker, N.

AU - Pankratz, V.S.

AU - Dickson, D.W.

AU - Graff-Radford, N.R.

AU - Petersen, R.C.

AU - Wright, A.F.

AU - Younkin, S.G.

AU - Morgan, K.

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Y1 - 2010/1/19

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JO - PLoS ONE

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M1 - e8764

ER -

Concordant Association of Insulin Degrading Enzyme Gene (IDE) Variants with IDE mRNA, A beta, and Alzheimer's Disease

Abstract

ASJC Scopus subject areas

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