Copper/TEMPO catalysed synthesis of nitriles from aldehydes or alcohols using aqueous ammonia and with air as the oxidant†‡

Laura M. Dornan, Qun Cao, James C. A. Flanagan, James J. Crawford, Matthew J. Cook, Mark J. Muldoon

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Abstract

Copper/TEMPO catalysts can be used to prepare nitriles from aldehydes or alcohols using aqueous ammonia. Readily accessible methods were developed that enable standard glassware to be used with air as the source of O2. It was further shown that, at higher temperatures in a pressurised reactor under limiting oxygen conditions (8% O2), catalyst loadings of 1 mol% could be employed.
Original languageEnglish
Pages (from-to)6030-6032
Number of pages3
JournalChemical Communications
Volume49
Issue number54
Early online date23 May 2013
DOIs
Publication statusPublished - 2013

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Keywords

  • Catalysis, organic chemistry, inorganic chemistry

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