Correlation of synovial fluid cytokine levels with histological and clinical parameters of primary and revision total hip and total knee replacements

Susan Clarke, R.A. Brooks, J.L. Hobby, J.A. Wimhurst, B.J. Myer, N. Rushton

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We retrieved synovial tissue and fluid samples from patients undergoing primary total hip replacement (THR) (n 15), revision of aseptically loose THR (n 12), primary total knee replacement (TKR) (n 13) and revision of aseptically loose TKR (n 6). Several histological parameters were assessed on a relative scale of 1-4. Primary TJRs were clinically evaluated for degree of osteoarthrosis. Revision TJRs were assessed for migration of the implant, gross loosening and the degree of radiolucency. Cytokine levels in synovial fluid were determined with ELISA.
Original languageEnglish
Pages (from-to)491-498
Number of pages8
JournalActa Orthopaedica Scandinavica
Volume72
Issue number5
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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