Cortisol, behavior, and heart rate reactivity to immunization pain at 4 months corrected age in infants born very preterm

Ruth E Grunau, Mai Thanh Tu, Michael F Whitfield, Tim F Oberlander, Joanne Weinberg, Wayne Yu, Paul Thiessen, Gisela Gosse, David Scheifele

Research output: Contribution to journalArticlepeer-review

56 Citations (Scopus)

Abstract

Pain response may be altered in infants born very preterm owing to repeated exposure to procedures in the neonatal intensive care unit. Findings have been inconsistent in studies of behavioral and cardiac responses to brief pain in preterm versus full-term infants following neonatal intensive care unit discharge. To our knowledge, cortisol reactivity to pain has not been compared in preterm and full-term infants. We examined pain reactivity to immunization in preterm and full-term infants.
Original languageEnglish
Pages (from-to)698-704
Number of pages7
JournalThe Clinical journal of pain
Volume26
Issue number8
DOIs
Publication statusPublished - 2010

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