Critical care ATLAS CLOVERS

Kelsey D. Sack; Chandrashish Chakravarty; Juliana Carvalho Ferreira; Daniela Helena Machado Freitas; Chris McGrath; Mark E. Mikkelsen; Matteo Di Nardo; Elisabeth Riviello; Michael Root; Jon A. Silversides; Theogene Twagirumugabe; Doris Uwamahoro

doi:10.1016/j.chstcc.2023.100043

Critical care ATLAS CLOVERS

Kelsey D. Sack^*
, Chandrashish Chakravarty
, Juliana Carvalho Ferreira
, Daniela Helena Machado Freitas
, Chris McGrath
, Mark E. Mikkelsen
, Matteo Di Nardo
, Elisabeth Riviello
, Michael Root
, Jon A. Silversides
, Theogene Twagirumugabe
, Doris Uwamahoro

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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Abstract

The practice of critical care is dependent not only on the particular patient population served but also the context in which critical care is provided, including culture and regional norms and resources. How clinicians interpret and implement new evidence or guideline recommendations is affected by their unique context. In 2023, the CLOVERS trial was published. The CLOVERS trial was a trial of 1563 patients which studied early vasopressor initiation versus liberal fluid initiation after an initial fluid bolus for patients presenting in the United States with septic shock. No mortality difference was found between the two treatment arms. In this article, adult and pediatric critical care clinicians from USA, UK, Italy, Rwanda, India, and Brazil describe how CLOVERS has impacted or will impact their practice.

Original language	English
Article number	100043
Number of pages	8
Journal	CHEST Critical Care
Volume	2
Issue number	1
Early online date	23 Dec 2023
DOIs	https://doi.org/10.1016/j.chstcc.2023.100043
Publication status	Published - Mar 2024

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Critical care ATLAS CLOVERS
Copyright 2024 The Authors. This is an open access article published under a Creative Commons Attribution-NonCommercial-NoDerivatives License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits distribution and reproduction for non-commercial purposes, provided the author and source are cited.
Final published version, 442 KBLicence: CC BY-NC-ND

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title = "Critical care ATLAS CLOVERS",

abstract = "The practice of critical care is dependent not only on the particular patient population served but also the context in which critical care is provided, including culture and regional norms and resources. How clinicians interpret and implement new evidence or guideline recommendations is affected by their unique context. In 2023, the CLOVERS trial was published. The CLOVERS trial was a trial of 1563 patients which studied early vasopressor initiation versus liberal fluid initiation after an initial fluid bolus for patients presenting in the United States with septic shock. No mortality difference was found between the two treatment arms. In this article, adult and pediatric critical care clinicians from USA, UK, Italy, Rwanda, India, and Brazil describe how CLOVERS has impacted or will impact their practice. ",

author = "Sack, \{Kelsey D.\} and Chandrashish Chakravarty and \{Carvalho Ferreira\}, Juliana and \{Machado Freitas\}, \{Daniela Helena\} and Chris McGrath and Mikkelsen, \{Mark E.\} and \{Di Nardo\}, Matteo and Elisabeth Riviello and Michael Root and Silversides, \{Jon A.\} and Theogene Twagirumugabe and Doris Uwamahoro",

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doi = "10.1016/j.chstcc.2023.100043",

language = "English",

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AU - Sack, Kelsey D.

AU - Chakravarty, Chandrashish

AU - Carvalho Ferreira, Juliana

AU - Machado Freitas, Daniela Helena

AU - McGrath, Chris

AU - Mikkelsen, Mark E.

AU - Di Nardo, Matteo

AU - Riviello, Elisabeth

AU - Root, Michael

AU - Silversides, Jon A.

AU - Twagirumugabe, Theogene

AU - Uwamahoro, Doris

PY - 2024/3

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AB - The practice of critical care is dependent not only on the particular patient population served but also the context in which critical care is provided, including culture and regional norms and resources. How clinicians interpret and implement new evidence or guideline recommendations is affected by their unique context. In 2023, the CLOVERS trial was published. The CLOVERS trial was a trial of 1563 patients which studied early vasopressor initiation versus liberal fluid initiation after an initial fluid bolus for patients presenting in the United States with septic shock. No mortality difference was found between the two treatment arms. In this article, adult and pediatric critical care clinicians from USA, UK, Italy, Rwanda, India, and Brazil describe how CLOVERS has impacted or will impact their practice.

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M3 - Article

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JO - CHEST Critical Care

JF - CHEST Critical Care

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ER -

Critical care ATLAS CLOVERS

Abstract

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