Critical Review: Injectability of Calcium Phosphate Pastes and Cements

R O'Neill, HO McCarthy, E Montufar, M-P Ginebra, DI Wilson, A Lennon, N Dunne

Research output: Contribution to journalReview articlepeer-review

179 Citations (Scopus)
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Calcium phosphate cements (CPC) have seen clinical success in many dental and orthopaedic applications in recent years. The properties of CPC essential for clinical success are reviewed in this article, which includes properties of the set cement (e.g. bioresorbability, biocompatibility, porosity and mechanical properties) and unset cement (e.g. setting time, cohesion, flow properties and ease of delivery to the surgical site). Emphasis is on the delivery of calcium phosphate (CaP) pastes and CPC, in particular the occurrence of separation of the liquid and solid components of the pastes and cements during injection; and established methods to reduce this phase separation. In addition a review of phase separation mechanisms observed during the extrusion of other biphasic paste systems and the theoretical models used to describe these mechanisms are discussed.
Original languageEnglish
Pages (from-to)1
Number of pages19
JournalActa Biomaterialia
Early online date09 Nov 2016
Publication statusPublished - 01 Mar 2017


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