Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury

E.J. Seeley, Danny McAuley, M. Eisner, M. Miletin, H.J. Zhuo, M.A. Matthay, R.H. Kallet

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: Multiple studies have identified single variables or composite scores that help risk stratify patients at the time of acute lung injury (ALI) diagnosis. However, few studies have addressed the important question of how changes in pulmonary physiologic variables might predict mortality in patients during the subacute or chronic phases of ALI. We studied pulmonary physiologic variables, including respiratory system compliance, P/F ratio and oxygenation index, in a cohort of patients with ALI who survived more than 6 days of mechanical ventilation to see if changes in these variables were predictive of death and whether they are informative about the pathophysiology of subacute ALI.
Original languageEnglish
Article number52
Pages (from-to)52
Number of pages1
JournalRespiratory Research
Volume12
DOIs
Publication statusPublished - 22 Apr 2011

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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