Abstract
Background: Male Irs2(-/-) mice develop fatal type 2 diabetes at 13-14 weeks. Defects in neuronal proliferation, pituitary development and photoreceptor cell survival manifest in Irs2(-/-) mice. We identify retarded renal growth in male and female Irs2(-/-) mice, independent of diabetes.
Original language | English |
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Article number | 73 |
Number of pages | 8 |
Journal | BMC Developmental Biology |
Volume | 10 |
DOIs | |
Publication status | Published - 2010 |
ASJC Scopus subject areas
- Developmental Biology