Depression associates with Mini Nutritional Assessment (MNA), Vitamin B12 and Folate status: Findings from Belfast Elderly Longitudinal Free-Living Ageing STudy (BELFAST)

Mark A Bowman, Jennifer Nicola M Rea, Ann Murphy , Maeve Rea

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Introduction: An association between depression and folate has been found in clinical studies. Depression and dementia can contribute to nutritional deficiency. This study clinical depression in in octo/nonagenarians from the BELFAST study.
Method: In the BELFAST study, 38 free-living octo/nonagenarians (mean age 82 years), who apparently well and cognitively intact were followed up at 5 years and assessed using the Geriatric Depression Scale (GDS), Folstein (30 point), Mini Nutritional Assessment Tool (MNA) together with serum folate and vitamin B12 levels.
Results: Mean GDS was 3.4 (SD 2.5), serum folate 7.1 umol/l (SD 5.3) and B12 553 umol/l (458). With mean MNA and Folstein -25.8 (SD 2.7) and 27.6 (SD 2.7) respectively with no sex difference (p = 0.78; p = 0.36). 25% of subjects showed a GDS >5 indicating risk of mild depression and 21% had compromised nutritional status. MNA associated with GDS in male (r2 = 0.56 p = 0.01), but not in female elderly subjects (r2 = 0.01; p = 0.44). GDS score and lower serum folate were associated (r2 = -0.23; p = 0.01).
Conclusion: Overall there was the suggestion that nutritional status and depression might be linked in male subjects at 5 year follow-up in octo/nonagenarians from the BEFLAST study. The lower folate in subjects categorised at risk of mild depression might suggest vitamin supplementation could be useful.
Original languageEnglish
Title of host publicationAge and Ageing
EditorsRoger Francis
PublisherOxford University Press
Volume42 Supp (2) ii1
ISBN (Electronic)ISSN 1468-2834
ISBN (Print)ISSN 0002-0729
DOIs
Publication statusPublished - 01 Mar 2013
EventBritish Geriatrics Society Autumn Meeting - Harrogate, United Kingdom
Duration: 28 Nov 201230 Nov 2012

Publication series

NameAge and Ageing
PublisherOxford University Press
Number2;ii1
Volume42
ISSN (Print)0002-0729
ISSN (Electronic)1468-2834

Conference

ConferenceBritish Geriatrics Society Autumn Meeting
CountryUnited Kingdom
CityHarrogate
Period28/11/201230/11/2012

Keywords

  • Ageing, MNA, Depression

Fingerprint

Dive into the research topics of 'Depression associates with Mini Nutritional Assessment (MNA), Vitamin B12 and Folate status: Findings from Belfast Elderly Longitudinal Free-Living Ageing STudy (BELFAST)'. Together they form a unique fingerprint.

Cite this