Detection of BRAF V600E mutation by pyrosequencing

Y.H. Tan; Y.Q. Liu; K.W. Eu; P.W. Ang; W.Q. Li; Manuel Salto-Tellez; B. Iacopetta; R. Soong

doi:10.1080/00313020801911512

Detection of BRAF V600E mutation by pyrosequencing

Y.H. Tan, Y.Q. Liu, K.W. Eu, P.W. Ang, W.Q. Li, Manuel Salto-Tellez, B. Iacopetta, R. Soong

Research output: Contribution to journal › Article › peer-review

82 Citations (Scopus)

Abstract

Introduction: Detection of the V600E hotspot mutation in BRAF oncogene is extremely useful for the screening of hereditary non-polyposis colorectal cancer (Lynch's syndrome) and for the prediction of sensitivity to MEK inhibitors. Here we describe a method for detecting this mutation based upon pyrosequencing technology.

Original language	English
Pages (from-to)	295-298
Number of pages	4
Journal	Pathology
Volume	40
Issue number	3
DOIs	https://doi.org/10.1080/00313020801911512
Publication status	Published - Mar 2008

ASJC Scopus subject areas

Pathology and Forensic Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/00313020801911512

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title = "Detection of BRAF V600E mutation by pyrosequencing",

abstract = "Introduction: Detection of the V600E hotspot mutation in BRAF oncogene is extremely useful for the screening of hereditary non-polyposis colorectal cancer (Lynch's syndrome) and for the prediction of sensitivity to MEK inhibitors. Here we describe a method for detecting this mutation based upon pyrosequencing technology.",

author = "Y.H. Tan and Y.Q. Liu and K.W. Eu and P.W. Ang and W.Q. Li and Manuel Salto-Tellez and B. Iacopetta and R. Soong",

year = "2008",

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doi = "10.1080/00313020801911512",

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T1 - Detection of BRAF V600E mutation by pyrosequencing

AU - Tan, Y.H.

AU - Liu, Y.Q.

AU - Eu, K.W.

AU - Ang, P.W.

AU - Li, W.Q.

AU - Salto-Tellez, Manuel

AU - Iacopetta, B.

AU - Soong, R.

PY - 2008/3

Y1 - 2008/3

N2 - Introduction: Detection of the V600E hotspot mutation in BRAF oncogene is extremely useful for the screening of hereditary non-polyposis colorectal cancer (Lynch's syndrome) and for the prediction of sensitivity to MEK inhibitors. Here we describe a method for detecting this mutation based upon pyrosequencing technology.

AB - Introduction: Detection of the V600E hotspot mutation in BRAF oncogene is extremely useful for the screening of hereditary non-polyposis colorectal cancer (Lynch's syndrome) and for the prediction of sensitivity to MEK inhibitors. Here we describe a method for detecting this mutation based upon pyrosequencing technology.

U2 - 10.1080/00313020801911512

DO - 10.1080/00313020801911512

M3 - Article

SN - 1465-3931

VL - 40

SP - 295

EP - 298

JO - Pathology

JF - Pathology

IS - 3

ER -

Detection of BRAF V600E mutation by pyrosequencing

Abstract

ASJC Scopus subject areas

UN SDGs

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