Detection of glycated gastric inhibitory polypeptide within the intestines of diabetic obese (ob/ob) mice

Mark Mooney, Y.H.A. Abdel-Wahab, L.M. Morgan, F.P.M. O'Harte, P.R. Flatt

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4 Citations (Scopus)

Abstract

Gastric inhibitory polypeptide (GIP) is produced within endocrine cells of the small intestine and released into the circulation upon nutrient ingestion. This study has quantified the levels of this insulinotropic peptide in the intestines of lean and diabetic obese ob/ob mice and estimated the proportion that is glycated. The total intestinal GIP concentration and content of the diabetic mice were significantly greater (p
Original languageEnglish
Pages (from-to)167-171
Number of pages5
JournalEndocrine
Volume16
Issue number3
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Endocrinology

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    Mooney, M., Abdel-Wahab, Y. H. A., Morgan, L. M., O'Harte, F. P. M., & Flatt, P. R. (2001). Detection of glycated gastric inhibitory polypeptide within the intestines of diabetic obese (ob/ob) mice. Endocrine, 16(3), 167-171.