Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, sichuan and shandong provinces, China, february 2019

Li Bai, Pengcheng Du, Yinju Du, Honghu Sun, Pei Zhang, Yuping Wan, Qi Lin, Séamus Fanning, Shenghui Cui, Yongning Wu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)
13 Downloads (Pure)

Abstract

The plasmid-mediated high-level tigecycline resistance gene, tet(X4), was detected in seven Escherichia coli isolates from pork in two Chinese provinces. Two isolates belonged to the epidemic spreading sequence type ST101. Tet(X4) was adjacent to ISVsa3 and concurrent with floR in all seven isolates. In addition to IncFIB, the replicon IncFII was found to be linked to tet(X4). This report follows a recent detection of tet(X3)/(X4) in E. coli from animals and humans in China.

Original languageEnglish
Article number1900340
JournalEurosurveillance
Volume24
Issue number25
DOIs
Publication statusPublished - 20 Jun 2019
Externally publishedYes

Bibliographical note

Funding Information:
We thank Prof. Yang Wang and Dr. Dejun Liu from Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University for the kind assistance and communication. Funding: This work was supported by the National Natural Science Foundation of China (31871899, 3181702038, 20837003 and 2166123031) and the National Key Research and Development Program of China (2017YFC1601502 and 2017YFE0110800) as well as European Union?s Horizon 2020 Research and Innovation Programme under Grant Agreement No 727864 EU-China-Safe

Funding Information:
Funding: This work was supported by the National Natural Science Foundation of China (31871899, 3181702038, 20837003 and 2166123031) and the National Key Research and Development Program of China (2017YFC1601502 and 2017YFE0110800) as well as European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement No 727864 EU-China-Safe.

Publisher Copyright:
© 2019, European Centre for Disease Prevention and Control (ECDC). All rights reserved.

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health
  • Virology

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