Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, sichuan and shandong provinces, China, february 2019

Li Bai; Pengcheng Du; Yinju Du; Honghu Sun; Pei Zhang; Yuping Wan; Qi Lin; Séamus Fanning; Shenghui Cui; Yongning Wu

doi:10.2807/1560-7917.ES.2019.24.25.1900340

Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, sichuan and shandong provinces, China, february 2019

Li Bai
, Pengcheng Du
, Yinju Du
, Honghu Sun
, Pei Zhang
, Yuping Wan
, Qi Lin
, Séamus Fanning
, Shenghui Cui
, Yongning Wu^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

86 Citations (Scopus)

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Abstract

The plasmid-mediated high-level tigecycline resistance gene, tet(X4), was detected in seven Escherichia coli isolates from pork in two Chinese provinces. Two isolates belonged to the epidemic spreading sequence type ST101. Tet(X4) was adjacent to ISVsa3 and concurrent with floR in all seven isolates. In addition to IncFIB, the replicon IncFII was found to be linked to tet(X4). This report follows a recent detection of tet(X3)/(X4) in E. coli from animals and humans in China.

Original language	English
Article number	1900340
Journal	Eurosurveillance
Volume	24
Issue number	25
DOIs	https://doi.org/10.2807/1560-7917.ES.2019.24.25.1900340
Publication status	Published - 20 Jun 2019
Externally published	Yes

Bibliographical note

Funding Information:
We thank Prof. Yang Wang and Dr. Dejun Liu from Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University for the kind assistance and communication. Funding: This work was supported by the National Natural Science Foundation of China (31871899, 3181702038, 20837003 and 2166123031) and the National Key Research and Development Program of China (2017YFC1601502 and 2017YFE0110800) as well as European Union?s Horizon 2020 Research and Innovation Programme under Grant Agreement No 727864 EU-China-Safe

Funding Information:
Funding: This work was supported by the National Natural Science Foundation of China (31871899, 3181702038, 20837003 and 2166123031) and the National Key Research and Development Program of China (2017YFC1601502 and 2017YFE0110800) as well as European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement No 727864 EU-China-Safe.

Publisher Copyright:
© 2019, European Centre for Disease Prevention and Control (ECDC). All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Epidemiology
Public Health, Environmental and Occupational Health
Virology

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10.2807/1560-7917.ES.2019.24.25.1900340Licence: CC BY

Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, Sichuan and Shandong Provinces, China, February 2019
Copyright 2019 the authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 282 KBLicence: CC BY

Cite this

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title = "Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, sichuan and shandong provinces, China, february 2019",

abstract = "The plasmid-mediated high-level tigecycline resistance gene, tet(X4), was detected in seven Escherichia coli isolates from pork in two Chinese provinces. Two isolates belonged to the epidemic spreading sequence type ST101. Tet(X4) was adjacent to ISVsa3 and concurrent with floR in all seven isolates. In addition to IncFIB, the replicon IncFII was found to be linked to tet(X4). This report follows a recent detection of tet(X3)/(X4) in E. coli from animals and humans in China.",

author = "Li Bai and Pengcheng Du and Yinju Du and Honghu Sun and Pei Zhang and Yuping Wan and Qi Lin and S{\'e}amus Fanning and Shenghui Cui and Yongning Wu",

note = "Funding Information: We thank Prof. Yang Wang and Dr. Dejun Liu from Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University for the kind assistance and communication. Funding: This work was supported by the National Natural Science Foundation of China (31871899, 3181702038, 20837003 and 2166123031) and the National Key Research and Development Program of China (2017YFC1601502 and 2017YFE0110800) as well as European Union?s Horizon 2020 Research and Innovation Programme under Grant Agreement No 727864 EU-China-Safe Funding Information: Funding: This work was supported by the National Natural Science Foundation of China (31871899, 3181702038, 20837003 and 2166123031) and the National Key Research and Development Program of China (2017YFC1601502 and 2017YFE0110800) as well as European Union{\textquoteright}s Horizon 2020 Research and Innovation Programme under Grant Agreement No 727864 EU-China-Safe. Publisher Copyright: {\textcopyright} 2019, European Centre for Disease Prevention and Control (ECDC). All rights reserved.",

year = "2019",

month = jun,

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doi = "10.2807/1560-7917.ES.2019.24.25.1900340",

language = "English",

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AU - Bai, Li

AU - Du, Pengcheng

AU - Du, Yinju

AU - Sun, Honghu

AU - Zhang, Pei

AU - Wan, Yuping

AU - Lin, Qi

AU - Fanning, Séamus

AU - Cui, Shenghui

AU - Wu, Yongning

N1 - Funding Information: We thank Prof. Yang Wang and Dr. Dejun Liu from Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University for the kind assistance and communication. Funding: This work was supported by the National Natural Science Foundation of China (31871899, 3181702038, 20837003 and 2166123031) and the National Key Research and Development Program of China (2017YFC1601502 and 2017YFE0110800) as well as European Union?s Horizon 2020 Research and Innovation Programme under Grant Agreement No 727864 EU-China-Safe Funding Information: Funding: This work was supported by the National Natural Science Foundation of China (31871899, 3181702038, 20837003 and 2166123031) and the National Key Research and Development Program of China (2017YFC1601502 and 2017YFE0110800) as well as European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement No 727864 EU-China-Safe. Publisher Copyright: © 2019, European Centre for Disease Prevention and Control (ECDC). All rights reserved.

PY - 2019/6/20

Y1 - 2019/6/20

N2 - The plasmid-mediated high-level tigecycline resistance gene, tet(X4), was detected in seven Escherichia coli isolates from pork in two Chinese provinces. Two isolates belonged to the epidemic spreading sequence type ST101. Tet(X4) was adjacent to ISVsa3 and concurrent with floR in all seven isolates. In addition to IncFIB, the replicon IncFII was found to be linked to tet(X4). This report follows a recent detection of tet(X3)/(X4) in E. coli from animals and humans in China.

AB - The plasmid-mediated high-level tigecycline resistance gene, tet(X4), was detected in seven Escherichia coli isolates from pork in two Chinese provinces. Two isolates belonged to the epidemic spreading sequence type ST101. Tet(X4) was adjacent to ISVsa3 and concurrent with floR in all seven isolates. In addition to IncFIB, the replicon IncFII was found to be linked to tet(X4). This report follows a recent detection of tet(X3)/(X4) in E. coli from animals and humans in China.

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Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, sichuan and shandong provinces, China, february 2019

Abstract

Bibliographical note

UN SDGs

ASJC Scopus subject areas

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