Development of a Portable Tissue Micro Array Instrument

K. K. Tan; A. S. Putra; L. P. Pham; T. H. Lee; M. Salto-Tellez; L. G. Kim

doi:10.1115/1.4004922

Development of a Portable Tissue Micro Array Instrument

K. K. Tan^*, A. S. Putra, L. P. Pham, T. H. Lee, M. Salto-Tellez, L. G. Kim

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Tissue micro array (TMA) is based on the idea of applying miniaturization and a high throughput approach to hybridization-based analyses of tissues. It facilitates biomedical research on a large scale in a single experiment; thus representing one of the most commonly used technologies in translational research. A critical analysis of the existing TMA instruments indicates that there are potential constraints in terms of portability, apart from costs and complexity. This paper will present the development of an affordable, configurable, and portable TMA instrument to allow an efficient collection of tissues, especially in instrument-to-tissue scenarios. The purely mechanical instrument requires no energy sources other than the user, is light weight, portable, and simple to use. [DOI: 10.1115/1.4004922]

Original language	English
Article number	ARTN 044503
Number of pages	7
Journal	Journal of medical devices-Transactions of the asme
Volume	5
Issue number	4
DOIs	https://doi.org/10.1115/1.4004922
Publication status	Published - Dec 2011

Keywords

MICROARRAYS
VALIDATION
bioMEMS
SYSTEM
portable instruments
CLASSIFICATION
EXPRESSION
CANCER
BLOCK
biomedical equipment
biological tissues
DISCOVERY

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1115/1.4004922

Cite this

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title = "Development of a Portable Tissue Micro Array Instrument",

abstract = "Tissue micro array (TMA) is based on the idea of applying miniaturization and a high throughput approach to hybridization-based analyses of tissues. It facilitates biomedical research on a large scale in a single experiment; thus representing one of the most commonly used technologies in translational research. A critical analysis of the existing TMA instruments indicates that there are potential constraints in terms of portability, apart from costs and complexity. This paper will present the development of an affordable, configurable, and portable TMA instrument to allow an efficient collection of tissues, especially in instrument-to-tissue scenarios. The purely mechanical instrument requires no energy sources other than the user, is light weight, portable, and simple to use. [DOI: 10.1115/1.4004922]",

keywords = "MICROARRAYS, VALIDATION, bioMEMS, SYSTEM, portable instruments, CLASSIFICATION, EXPRESSION, CANCER, BLOCK, biomedical equipment, biological tissues, DISCOVERY",

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year = "2011",

month = dec,

doi = "10.1115/1.4004922",

language = "English",

volume = "5",

journal = "Journal of medical devices-Transactions of the asme",

issn = "1932-6181",

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TY - JOUR

T1 - Development of a Portable Tissue Micro Array Instrument

AU - Tan, K. K.

AU - Putra, A. S.

AU - Pham, L. P.

AU - Lee, T. H.

AU - Salto-Tellez, M.

AU - Kim, L. G.

PY - 2011/12

Y1 - 2011/12

N2 - Tissue micro array (TMA) is based on the idea of applying miniaturization and a high throughput approach to hybridization-based analyses of tissues. It facilitates biomedical research on a large scale in a single experiment; thus representing one of the most commonly used technologies in translational research. A critical analysis of the existing TMA instruments indicates that there are potential constraints in terms of portability, apart from costs and complexity. This paper will present the development of an affordable, configurable, and portable TMA instrument to allow an efficient collection of tissues, especially in instrument-to-tissue scenarios. The purely mechanical instrument requires no energy sources other than the user, is light weight, portable, and simple to use. [DOI: 10.1115/1.4004922]

AB - Tissue micro array (TMA) is based on the idea of applying miniaturization and a high throughput approach to hybridization-based analyses of tissues. It facilitates biomedical research on a large scale in a single experiment; thus representing one of the most commonly used technologies in translational research. A critical analysis of the existing TMA instruments indicates that there are potential constraints in terms of portability, apart from costs and complexity. This paper will present the development of an affordable, configurable, and portable TMA instrument to allow an efficient collection of tissues, especially in instrument-to-tissue scenarios. The purely mechanical instrument requires no energy sources other than the user, is light weight, portable, and simple to use. [DOI: 10.1115/1.4004922]

KW - MICROARRAYS

KW - VALIDATION

KW - bioMEMS

KW - SYSTEM

KW - portable instruments

KW - CLASSIFICATION

KW - EXPRESSION

KW - CANCER

KW - BLOCK

KW - biomedical equipment

KW - biological tissues

KW - DISCOVERY

U2 - 10.1115/1.4004922

DO - 10.1115/1.4004922

M3 - Article

SN - 1932-6181

VL - 5

JO - Journal of medical devices-Transactions of the asme

JF - Journal of medical devices-Transactions of the asme

IS - 4

M1 - ARTN 044503

ER -

Development of a Portable Tissue Micro Array Instrument

Abstract

Keywords

UN SDGs

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