Development of an ELISA screening test for nitroimidazoles in egg and chicken muscle

Anne-Catherine Huet, L. Mortier, E. Daeseleire, Terence Fodey, Christopher Elliott, P. Delahaut

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)

Abstract

An antibody was generated that can bind metronidazole (MNZ), a nitroimidazole drug used in veterinary medicine to treat poultry for coccidiosis and histomoniasis. A direct competitive enzyme-linked immunosorbent assay (cELISA) is described. It was used to characterise binding of this antibody to a number of nitroimidazole drugs. It displayed cross-reactivity with dimetridazole (DMZ), ronidazole (RNZ), hydroxydimetridazole (DMZOH), and ipronidazole (IPZ).
Original languageEnglish
Pages (from-to)157-162
Number of pages6
JournalAnalytica Chimica Acta
Volume534
Issue number1
DOIs
Publication statusPublished - 04 Apr 2005

ASJC Scopus subject areas

  • Biochemistry
  • Analytical Chemistry
  • Spectroscopy
  • Environmental Chemistry

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