Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains

Guiya Deng; Ke Huang; Xianchao Jiang; Kun Wang; Zihao Song; Yuchen Su; Chengming Li; Shuai Zhang; Shiqi Wang; Yaqin Huang

doi:10.1186/s42825-023-00131-9

Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains

Guiya Deng, Ke Huang, Xianchao Jiang, Kun Wang, Zihao Song, Yuchen Su, Chengming Li, Shuai Zhang, Shiqi Wang^*, Yaqin Huang^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Review article › peer-review

9 Citations (Scopus)

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Abstract

Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field. In this review, we summarize recent advances in antioxidant collagen hydrolysates development. Initially, the preparation process of antioxidant collagen hydrolysates is introduced, including the production and separation methods. Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed. Finally, the applications of antioxidant collagen hydrolysates in biomedical domains are summarized, with critical discussions about the advantages, current limitations and challenges to be resolved in the future. Graphical abstract:

Original language	English
Journal	Collagen and Leather
Volume	5
Issue number	1
Early online date	26 Sept 2023
DOIs	https://doi.org/10.1186/s42825-023-00131-9
Publication status	Published - Dec 2023

Keywords

Biomedical applications
Peptides
Collagen hydrolysates
Antioxidant

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10.1186/s42825-023-00131-9Licence: CC BY

42825_2023_Article_131.pdfFinal published version, 2.86 MBLicence: CC BY

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title = "Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains",

abstract = "Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field. In this review, we summarize recent advances in antioxidant collagen hydrolysates development. Initially, the preparation process of antioxidant collagen hydrolysates is introduced, including the production and separation methods. Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed. Finally, the applications of antioxidant collagen hydrolysates in biomedical domains are summarized, with critical discussions about the advantages, current limitations and challenges to be resolved in the future. Graphical abstract:",

keywords = "Biomedical applications, Peptides, Collagen hydrolysates, Antioxidant",

author = "Guiya Deng and Ke Huang and Xianchao Jiang and Kun Wang and Zihao Song and Yuchen Su and Chengming Li and Shuai Zhang and Shiqi Wang and Yaqin Huang",

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doi = "10.1186/s42825-023-00131-9",

language = "English",

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T1 - Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains

AU - Deng, Guiya

AU - Huang, Ke

AU - Jiang, Xianchao

AU - Wang, Kun

AU - Song, Zihao

AU - Su, Yuchen

AU - Li, Chengming

AU - Zhang, Shuai

AU - Wang, Shiqi

AU - Huang, Yaqin

PY - 2023/12

Y1 - 2023/12

N2 - Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field. In this review, we summarize recent advances in antioxidant collagen hydrolysates development. Initially, the preparation process of antioxidant collagen hydrolysates is introduced, including the production and separation methods. Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed. Finally, the applications of antioxidant collagen hydrolysates in biomedical domains are summarized, with critical discussions about the advantages, current limitations and challenges to be resolved in the future. Graphical abstract:

AB - Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field. In this review, we summarize recent advances in antioxidant collagen hydrolysates development. Initially, the preparation process of antioxidant collagen hydrolysates is introduced, including the production and separation methods. Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed. Finally, the applications of antioxidant collagen hydrolysates in biomedical domains are summarized, with critical discussions about the advantages, current limitations and challenges to be resolved in the future. Graphical abstract:

KW - Biomedical applications

KW - Peptides

KW - Collagen hydrolysates

KW - Antioxidant

U2 - 10.1186/s42825-023-00131-9

DO - 10.1186/s42825-023-00131-9

M3 - Review article

SN - 2097-1419

VL - 5

JO - Collagen and Leather

JF - Collagen and Leather

IS - 1

ER -

Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains

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