Discordant quantitative detection of putative biomarkers in nodal micrometastases of colorectal cancer: biological and clinical implications

S.L. Kong; Manuel Salto-Tellez; A.P.K. Leong; Y.H. Chan; E.S.C. Koay

doi:10.1136/jcp.2004.023853

Discordant quantitative detection of putative biomarkers in nodal micrometastases of colorectal cancer: biological and clinical implications

S.L. Kong, Manuel Salto-Tellez, A.P.K. Leong, Y.H. Chan, E.S.C. Koay

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Aims: Nodal expression of the carcinoembryonic antigen ( CEA), cytokeratin 20 ( CK20), and guanylyl cyclase C ( GCC) genes was measured in tandem in patients with colorectal cancer ( CRC) to assess whether there would be sufficient agreement between these markers in their ability to detect micrometastasis to qualify one of them as a universal marker, and whether frozen and paraffin wax embedded tissues would yield similar results.

Original language	English
Pages (from-to)	839-844
Number of pages	6
Journal	Journal of Clinical Pathology
Volume	58
Issue number	8
DOIs	https://doi.org/10.1136/jcp.2004.023853
Publication status	Published - Aug 2005

ASJC Scopus subject areas

Pathology and Forensic Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1136/jcp.2004.023853

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title = "Discordant quantitative detection of putative biomarkers in nodal micrometastases of colorectal cancer: biological and clinical implications",

abstract = "Aims: Nodal expression of the carcinoembryonic antigen ( CEA), cytokeratin 20 ( CK20), and guanylyl cyclase C ( GCC) genes was measured in tandem in patients with colorectal cancer ( CRC) to assess whether there would be sufficient agreement between these markers in their ability to detect micrometastasis to qualify one of them as a universal marker, and whether frozen and paraffin wax embedded tissues would yield similar results.",

author = "S.L. Kong and Manuel Salto-Tellez and A.P.K. Leong and Y.H. Chan and E.S.C. Koay",

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AU - Kong, S.L.

AU - Salto-Tellez, Manuel

AU - Leong, A.P.K.

AU - Chan, Y.H.

AU - Koay, E.S.C.

PY - 2005/8

Y1 - 2005/8

N2 - Aims: Nodal expression of the carcinoembryonic antigen ( CEA), cytokeratin 20 ( CK20), and guanylyl cyclase C ( GCC) genes was measured in tandem in patients with colorectal cancer ( CRC) to assess whether there would be sufficient agreement between these markers in their ability to detect micrometastasis to qualify one of them as a universal marker, and whether frozen and paraffin wax embedded tissues would yield similar results.

AB - Aims: Nodal expression of the carcinoembryonic antigen ( CEA), cytokeratin 20 ( CK20), and guanylyl cyclase C ( GCC) genes was measured in tandem in patients with colorectal cancer ( CRC) to assess whether there would be sufficient agreement between these markers in their ability to detect micrometastasis to qualify one of them as a universal marker, and whether frozen and paraffin wax embedded tissues would yield similar results.

U2 - 10.1136/jcp.2004.023853

DO - 10.1136/jcp.2004.023853

M3 - Article

VL - 58

SP - 839

EP - 844

JO - Journal of Clinical Pathology

JF - Journal of Clinical Pathology

SN - 0021-9746

IS - 8

ER -

Discordant quantitative detection of putative biomarkers in nodal micrometastases of colorectal cancer: biological and clinical implications

Abstract

ASJC Scopus subject areas

UN SDGs

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