DNA damage by low-energy ions

C.A. Hunniford, Robert McCullough, R.J.H. Davies, D.J. Timson

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Ion-beam irradiation provides a promising treatment for some types of cancer. This promise is due mainly to the selective deposition of energy into a relatively small volume (the Bragg peak), thus reducing damage to healthy tissue. Recent observations that electrons with energies below the ionization potential of DNA can cause covalent damage to the bases and backbone have led to investigations into the ability of low-energy (
Original languageEnglish
Pages (from-to)893-896
Number of pages4
JournalBiochemical society transactions
Volume37
Issue number4
DOIs
Publication statusPublished - 01 Jan 2009

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