Domino Alkene-Isomerization–Claisen Rearrangement Strategy to Substituted Allylsilanes

Matthew Cook, Mark McLaughlin

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A one-pot isomerization–Claisen protocol has been developed for the synthesis of highly substituted allylsilanes. Monosilylated divinyl ethers can be isomerized using a cationic iridium(I) catalyst followed by a thermal Claisen rearrangement to provide the allylsilanes in excellent yields and diastereoselectivities.
Original languageEnglish
Pages (from-to)2058-2063
Number of pages6
JournalJournal of Organic Chemistry
Volume77
Issue number4
Early online date10 Jan 2012
DOIs
Publication statusPublished - 17 Feb 2012

ASJC Scopus subject areas

  • Organic Chemistry

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