Dysfunctional filtering blebs

A. Azuara-Blanco, L.J. Katz

Research output: Contribution to journalArticlepeer-review

198 Citations (Scopus)


Guarded filtration surgery is commonly used to control the intraocular pressure (IOP) in glaucomatous patients. Filtration surgery lowers the IOP by creating a fistula between the inner compartments of the eye and the subconjunctival space (i.e., filtering bleb). There are several options to improve the function of filtering blebs and to prevent their failure. However, improvement of IOP control after guarded filtration procedures is associated with a higher frequency of bleb-related complications. Early (e.g., bleb leak, excessive filtration, flat anterior chamber, filtration failure) and late (e.g., bleb leak, excessive filtration and hypotony, symptomatic blebs, bleb encapsulation, filtration failure, bleb infection) complications associated with filtering procedures should be managed adequately to prevent further problems. Techniques to improve the function of filtering blebs and to treat postoperative complications have progressed over the past decade.
Original languageEnglish
Pages (from-to)93-126
Number of pages34
JournalSurvey of ophthalmology
Issue number2
Publication statusPublished - 01 Sep 1998


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