Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome

J. Burn; D.T. Bishop; J.P. Mecklin; F. Macrae; G. Moslein; S. Olschwang; M.L. Bisgaard; R. Ramesar; D. Eccles; E.R. Maher; L. Bertario; H.J. Jarvinen; A. Lindblom; D.G. Evans; J. Lubinski; Patrick Morrison; J.W.C. Ho; H.F.A. Vasen; L. Side; H.J.W. Thomas; R.J. Scott; M. Dunlop; G. Barker; F. Elliott; J.R. Jass; R. Fodde; H.T. Lynch; J.C. Mathers

Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome

J. Burn, D.T. Bishop, J.P. Mecklin, F. Macrae, G. Moslein, S. Olschwang, M.L. Bisgaard, R. Ramesar, D. Eccles, E.R. Maher, L. Bertario, H.J. Jarvinen, A. Lindblom, D.G. Evans, J. Lubinski, Patrick Morrison, J.W.C. Ho, H.F.A. Vasen, L. Side, H.J.W. ThomasR.J. Scott, M. Dunlop, G. Barker, F. Elliott, J.R. Jass, R. Fodde, H.T. Lynch, J.C. Mathers

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

257 Citations (Scopus)

Abstract

Background: Observational and epidemiologic data indicate that the use of aspirin reduces the risk of colorectal neoplasia; however, the effects of aspirin in the Lynch syndrome (hereditary nonpolyposis colon cancer) are not known. Resistant starch has been associated with an antineoplastic effect on the colon.

Original language	English
Pages (from-to)	2567-2578
Number of pages	12
Journal	New England Journal of Medicine
Volume	359
Issue number	24
Publication status	Published - 11 Dec 2008

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

Burn, J., Bishop, D. T., Mecklin, J. P., Macrae, F., Moslein, G., Olschwang, S., Bisgaard, M. L., Ramesar, R., Eccles, D., Maher, E. R., Bertario, L., Jarvinen, H. J., Lindblom, A., Evans, D. G., Lubinski, J., Morrison, P., Ho, J. W. C., Vasen, H. F. A., Side, L., ... Mathers, J. C. (2008). Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome. New England Journal of Medicine, 359(24), 2567-2578.

@article{37a4618450904090b1d8bb653df2d3c9,

title = "Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome",

abstract = "Background: Observational and epidemiologic data indicate that the use of aspirin reduces the risk of colorectal neoplasia; however, the effects of aspirin in the Lynch syndrome (hereditary nonpolyposis colon cancer) are not known. Resistant starch has been associated with an antineoplastic effect on the colon.",

author = "J. Burn and D.T. Bishop and J.P. Mecklin and F. Macrae and G. Moslein and S. Olschwang and M.L. Bisgaard and R. Ramesar and D. Eccles and E.R. Maher and L. Bertario and H.J. Jarvinen and A. Lindblom and D.G. Evans and J. Lubinski and Patrick Morrison and J.W.C. Ho and H.F.A. Vasen and L. Side and H.J.W. Thomas and R.J. Scott and M. Dunlop and G. Barker and F. Elliott and J.R. Jass and R. Fodde and H.T. Lynch and J.C. Mathers",

year = "2008",

month = dec,

day = "11",

language = "English",

volume = "359",

pages = "2567--2578",

journal = "New England Journal of Medicine",

publisher = "Massachusetts Medical Society",

number = "24",

}

Burn, J, Bishop, DT, Mecklin, JP, Macrae, F, Moslein, G, Olschwang, S, Bisgaard, ML, Ramesar, R, Eccles, D, Maher, ER, Bertario, L, Jarvinen, HJ, Lindblom, A, Evans, DG, Lubinski, J, Morrison, P, Ho, JWC, Vasen, HFA, Side, L, Thomas, HJW, Scott, RJ, Dunlop, M, Barker, G, Elliott, F, Jass, JR, Fodde, R, Lynch, HT & Mathers, JC 2008, 'Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome', New England Journal of Medicine, vol. 359, no. 24, pp. 2567-2578.

TY - JOUR

T1 - Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome

AU - Burn, J.

AU - Bishop, D.T.

AU - Mecklin, J.P.

AU - Macrae, F.

AU - Moslein, G.

AU - Olschwang, S.

AU - Bisgaard, M.L.

AU - Ramesar, R.

AU - Eccles, D.

AU - Maher, E.R.

AU - Bertario, L.

AU - Jarvinen, H.J.

AU - Lindblom, A.

AU - Evans, D.G.

AU - Lubinski, J.

AU - Morrison, Patrick

AU - Ho, J.W.C.

AU - Vasen, H.F.A.

AU - Side, L.

AU - Thomas, H.J.W.

AU - Scott, R.J.

AU - Dunlop, M.

AU - Barker, G.

AU - Elliott, F.

AU - Jass, J.R.

AU - Fodde, R.

AU - Lynch, H.T.

AU - Mathers, J.C.

PY - 2008/12/11

Y1 - 2008/12/11

N2 - Background: Observational and epidemiologic data indicate that the use of aspirin reduces the risk of colorectal neoplasia; however, the effects of aspirin in the Lynch syndrome (hereditary nonpolyposis colon cancer) are not known. Resistant starch has been associated with an antineoplastic effect on the colon.

AB - Background: Observational and epidemiologic data indicate that the use of aspirin reduces the risk of colorectal neoplasia; however, the effects of aspirin in the Lynch syndrome (hereditary nonpolyposis colon cancer) are not known. Resistant starch has been associated with an antineoplastic effect on the colon.

M3 - Article

VL - 359

SP - 2567

EP - 2578

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 24

ER -

Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome

Abstract

ASJC Scopus subject areas

UN SDGs

Fingerprint

Cite this