Effect of genotype on changes in intelligence quotient after dietary relaxation in phenylketonuria and hyperphenylalaninaemia

L.G. Greeves, Christopher Patterson, Dennis Carson, R. Thom, M.C. Wolfenden, J. Zschocke, Colin Graham, Norman Nevin, Elizabeth Trimble

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background-Associations between genotype and intellectual outcome in patients with phenylketonuria are complicated because intelligence is influenced by many variables, including environmental factors and other genetic determinants. Intellectual changes with age, both on and after relaxation of diet, vary within the patient population. This study aims to determine whether a significant association exists between genotype and change in intelligence after relaxation of diet.
Original languageEnglish
Pages (from-to)216-221
Number of pages6
JournalArchives of Disease in Childhood
Volume82
Issue number3
Publication statusPublished - 2000

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Phenylketonurias
Intelligence
Genotype
Diet
Population

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Greeves, L.G. ; Patterson, Christopher ; Carson, Dennis ; Thom, R. ; Wolfenden, M.C. ; Zschocke, J. ; Graham, Colin ; Nevin, Norman ; Trimble, Elizabeth. / Effect of genotype on changes in intelligence quotient after dietary relaxation in phenylketonuria and hyperphenylalaninaemia. In: Archives of Disease in Childhood. 2000 ; Vol. 82, No. 3. pp. 216-221.
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Effect of genotype on changes in intelligence quotient after dietary relaxation in phenylketonuria and hyperphenylalaninaemia. / Greeves, L.G.; Patterson, Christopher; Carson, Dennis; Thom, R.; Wolfenden, M.C.; Zschocke, J.; Graham, Colin; Nevin, Norman; Trimble, Elizabeth.

In: Archives of Disease in Childhood, Vol. 82, No. 3, 2000, p. 216-221.

Research output: Contribution to journalArticle

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AU - Greeves, L.G.

AU - Patterson, Christopher

AU - Carson, Dennis

AU - Thom, R.

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AU - Zschocke, J.

AU - Graham, Colin

AU - Nevin, Norman

AU - Trimble, Elizabeth

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