EFFECT OF IMPELLER DESIGN ON PRODUCT HOMOGENIETY IN HIGH SHEAR WET GRANULATION

Zakaria Mirza, Chirangano Mangwandi, Gavin Walker

Research output: Contribution to conferencePaper

Abstract

Design of small mixer impellers is not tailored for granulation as they are designed for a wide range of processes. The Kenwood KM070 was employed as a standard apparatus to undertake this investigation. Five different impeller designs were used, possessing different shapes and surface areas. The aim of this research was to evaluate the performances of these impellers to provide
guidance on the selection and design for the purposes of granulation. Lactose granules were produced using wet granulation with water as the binder.
The efficacy of respective granulates was measured by adding an optically
sensitive tracer.This was used to determine powder concentrations
within various regions of the granulator. It was found that impeller design influenced the homogeneity of the granules; and therefore can affect final product performance.
Original languageEnglish
Publication statusPublished - 26 Jun 2013
Event6th International Granulation Workshop - Sheffield, United Kingdom
Duration: 25 Jul 201228 Jul 2012

Conference

Conference6th International Granulation Workshop
CountryUnited Kingdom
CitySheffield
Period25/07/201228/07/2012

Fingerprint

Granulation
Impellers
Granulators
Binders
Powders
Water

Keywords

  • Granulation
  • homogeniety
  • Granular flow
  • impeller speed

Cite this

Mirza, Z., Mangwandi, C., & Walker, G. (2013). EFFECT OF IMPELLER DESIGN ON PRODUCT HOMOGENIETY IN HIGH SHEAR WET GRANULATION. Paper presented at 6th International Granulation Workshop, Sheffield, United Kingdom.
Mirza, Zakaria ; Mangwandi, Chirangano ; Walker, Gavin. / EFFECT OF IMPELLER DESIGN ON PRODUCT HOMOGENIETY IN HIGH SHEAR WET GRANULATION. Paper presented at 6th International Granulation Workshop, Sheffield, United Kingdom.
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Mirza, Z, Mangwandi, C & Walker, G 2013, 'EFFECT OF IMPELLER DESIGN ON PRODUCT HOMOGENIETY IN HIGH SHEAR WET GRANULATION', Paper presented at 6th International Granulation Workshop, Sheffield, United Kingdom, 25/07/2012 - 28/07/2012.

EFFECT OF IMPELLER DESIGN ON PRODUCT HOMOGENIETY IN HIGH SHEAR WET GRANULATION. / Mirza, Zakaria; Mangwandi, Chirangano; Walker, Gavin.

2013. Paper presented at 6th International Granulation Workshop, Sheffield, United Kingdom.

Research output: Contribution to conferencePaper

TY - CONF

T1 - EFFECT OF IMPELLER DESIGN ON PRODUCT HOMOGENIETY IN HIGH SHEAR WET GRANULATION

AU - Mirza, Zakaria

AU - Mangwandi, Chirangano

AU - Walker, Gavin

PY - 2013/6/26

Y1 - 2013/6/26

N2 - Design of small mixer impellers is not tailored for granulation as they are designed for a wide range of processes. The Kenwood KM070 was employed as a standard apparatus to undertake this investigation. Five different impeller designs were used, possessing different shapes and surface areas. The aim of this research was to evaluate the performances of these impellers to provideguidance on the selection and design for the purposes of granulation. Lactose granules were produced using wet granulation with water as the binder.The efficacy of respective granulates was measured by adding an opticallysensitive tracer.This was used to determine powder concentrationswithin various regions of the granulator. It was found that impeller design influenced the homogeneity of the granules; and therefore can affect final product performance.

AB - Design of small mixer impellers is not tailored for granulation as they are designed for a wide range of processes. The Kenwood KM070 was employed as a standard apparatus to undertake this investigation. Five different impeller designs were used, possessing different shapes and surface areas. The aim of this research was to evaluate the performances of these impellers to provideguidance on the selection and design for the purposes of granulation. Lactose granules were produced using wet granulation with water as the binder.The efficacy of respective granulates was measured by adding an opticallysensitive tracer.This was used to determine powder concentrationswithin various regions of the granulator. It was found that impeller design influenced the homogeneity of the granules; and therefore can affect final product performance.

KW - Granulation

KW - homogeniety

KW - Granular flow

KW - impeller speed

M3 - Paper

ER -

Mirza Z, Mangwandi C, Walker G. EFFECT OF IMPELLER DESIGN ON PRODUCT HOMOGENIETY IN HIGH SHEAR WET GRANULATION. 2013. Paper presented at 6th International Granulation Workshop, Sheffield, United Kingdom.