Abstract
Type 1 diabetes mellitus is associated with an increased risk of cardiovascular disease (CVD) that is not fully explained by conventional risk factors. The Diabetes Control and Complications Trial (DCCT) showed that intensive diabetes therapy reduced levels of LDL cholesterol and triglycerides but increased the risk of major weight gain, which might adversely affect CVD risk. The present study examined the effect of intensive therapy on levels of several markers of inflammation that have been linked to risk of CVD.
Original language | English |
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Pages (from-to) | 2446-53 |
Number of pages | 8 |
Journal | Circulation |
Volume | 111 |
Issue number | 19 |
DOIs | |
Publication status | Published - 17 May 2005 |
Keywords
- Adolescent
- Adult
- Biological Markers
- Cardiovascular Diseases
- Diabetes Mellitus, Type 1
- Diabetic Angiopathies
- Female
- Humans
- Hypoglycemic Agents
- Inflammation
- Insulin
- Male
- Risk Factors
- Weight Gain