Effects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 omicron infections

Suelen H Qassim, Hiam Chemaitelly, Houssein H Ayoub, Sawsan AlMukdad, Patrick Tang, Mohammad R Hasan, Hadi M Yassine, Hebah A Al-Khatib, Maria K Smatti, Hanan F Abdul-Rahim, Gheyath K Nasrallah, Mohamed Ghaith Al-Kuwari, Abdullatif Al-Khal, Peter Coyle, Anvar Hassan Kaleeckal, Riyazuddin Mohammad Shaik, Ali Nizar Latif, Einas Al-Kuwari, Andrew Jeremijenko, Adeel A ButtRoberto Bertollini, Hamad Eid Al-Romaihi, Mohamed H Al-Thani, Laith J Abu-Raddad

Research output: Contribution to journalArticlepeer-review

Abstract

Compared to BA.1, BA.2 was associated with lower RT-qPCR cycle threshold (Ct) value—3.53 fewer cycles (95% CI: 3.46–3.60), signifying higher infectiousness. This may reflect higher viral load and/or longer duration of infection for BA.2. Natural immunity from previous infection and booster vaccination were associated with less infectious breakthrough infections.
Original languageEnglish
JournalJournal of Travel Medicine
Early online date27 May 2022
DOIs
Publication statusEarly online date - 27 May 2022

Keywords

  • General Medicine

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