Effects of low energy carbon ions on plasmid DNA

C.A. Hunniford; D.J. Timson; R.J.H. Davies; Robert McCullough

doi:10.1088/1742-6596/101/1/012012

Effects of low energy carbon ions on plasmid DNA

C.A. Hunniford, D.J. Timson, R.J.H. Davies, Robert McCullough

School of Mathematics and Physics

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4 Citations (Scopus)

Abstract

The damage induced in supercoiled plasmid DNA molecules by low energy (< 1 keV u-1) singly and doubly charged carbon ions has been investigated as a function of ion exposure. The production of short linear fragments through multiple double strand breakage is indicated and exponential exposure responses for each of the topoisomers are presented. The damage produced by C2+ is apparent at much lower ion exposures that with C+.

Original language	English
Article number	012012
Journal	Journal of Physics: Conference Series
Volume	101
Issue number	1
DOIs	https://doi.org/10.1088/1742-6596/101/1/012012
Publication status	Published - Jul 2008
Event	Radiation Damage in Biomolecular Systems - Dublin, Ireland Duration: 01 Jul 2008 → 01 Jul 2008

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10.1088/1742-6596/101/1/012012

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author = "C.A. Hunniford and D.J. Timson and R.J.H. Davies and Robert McCullough",

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AU - Timson, D.J.

AU - Davies, R.J.H.

AU - McCullough, Robert

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AB - The damage induced in supercoiled plasmid DNA molecules by low energy (< 1 keV u-1) singly and doubly charged carbon ions has been investigated as a function of ion exposure. The production of short linear fragments through multiple double strand breakage is indicated and exponential exposure responses for each of the topoisomers are presented. The damage produced by C2+ is apparent at much lower ion exposures that with C+.

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Effects of low energy carbon ions on plasmid DNA

Abstract

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