Modified (oxidized and/or glycated) low-density lipoproteins (LDLs) have been implicated in retinal pericyte loss, one of the major pathologic features of early-stage diabetic retinopathy. To delineate underlying molecular mechanisms, the present study was designed to explore the global effects of modified LDL on pericyte gene expression.
- Gene Expression
- Gene Expression Profiling
- Lipoproteins, LDL
- Oligonucleotide Array Sequence Analysis
- Retinal Vessels
- Reverse Transcriptase Polymerase Chain Reaction