ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams

Giuseppe A.P. Cirrone; Giada Petringa; Roberto Catalano; Francesco Schillaci; Luciano Allegra; Antonino Amato; Renato Avolio; Michele Costa; Giacomo Cuttone; Antonin Fajstavr; Giuseppe Gallo; Lorenzo Giuffrida; Mariacristina Guarrera; Georg Korn; Giuseppina Larosa; Renata Leanza; Enzo Lo Vecchio; Gustavo Messina; Giuliana Milluzzo; Veronika Olsovcova; Salvatore Pulvirenti; Jan Pipek; Francesco Romano; Daniele Rizzo; Antonio D. Russo; S. Salamone; Valentina Scuderi; Andriy Velyhan; Salvatore Vinciguerra; Martina Zakova; Emilio Zappalà; Daniele Margarone

doi:10.3389/fphy.2020.564907

ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams

Giuseppe A.P. Cirrone^*, Giada Petringa, Roberto Catalano, Francesco Schillaci, Luciano Allegra, Antonino Amato, Renato Avolio, Michele Costa, Giacomo Cuttone, Antonin Fajstavr, Giuseppe Gallo, Lorenzo Giuffrida, Mariacristina Guarrera, Georg Korn, Giuseppina Larosa, Renata Leanza, Enzo Lo Vecchio, Gustavo Messina, Giuliana Milluzzo, Veronika OlsovcovaSalvatore Pulvirenti, Jan Pipek, Francesco Romano, Daniele Rizzo, Antonio D. Russo, S. Salamone, Valentina Scuderi, Andriy Velyhan, Salvatore Vinciguerra, Martina Zakova, Emilio Zappalà, Daniele Margarone

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

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Abstract

The main effort of the laser-driven ion acceleration community is aimed at improving particle beam features (in terms of final maximum energy, particle charge, and beam divergence) and to demonstrate reliable approaches for use for multidisciplinary applications. An ion acceleration target area based on unique laser capabilities is available at ELI-Beamlines (Extreme Light Infrastructure) in the Czech Republic; it is called ELIMAIA (ELI Multidisciplinary Applications of laser-Ion Acceleration) and aims to provide stable and characterized beams of particles accelerated by high-power lasers to offer them to the user community for interdisciplinary studies. The ELIMAIA section dedicated to ion focusing, selection, characterization, and irradiation is named ELIMED (ELI MEDical and multidisciplinary applications). Thanks to ELIMED, very high-dose-rate (around Gy/min) controlled proton and ion beams, with energy levels ranging from 5 to 250 MeV, will be transported to an in-air section dedicated to absolute and relative dosimetry of the laser-generated ions. A transmission dual-gap air ionization chamber will allow an on-line, non-destructive characterization of the ion dose at the user sample irradiation point. The uncertainty in the final dose released onto the sample is expected to be well below 5%. An ELIMED radiobiology pilot experiment is scheduled for 2021, during which in-vitro cell irradiations will be carried out with well-controlled proton beams. In this work, the status of the ELIMED/ELIMAIA beamline will be described along with a complete definition of the main dosimetric systems and of their calibrations carried out at conventional accelerators.

Original language	English
Article number	564907
Number of pages	8
Journal	Frontiers in Physics
Volume	8
DOIs	https://doi.org/10.3389/fphy.2020.564907
Publication status	Published - 13 Nov 2020

Bibliographical note

Funding Information:
Funding. This work has been supported by the project ELI?Extreme Light Infrastructure?phase 2 (CZ.02.1.01/0.0/0.0/15-008/0000162) from European Regional Development Fund, by the Ministry of Education, Youth and Sports of the Czech Republic (Project No. LQ1606) and by the project Advanced Research Using High Intensity Laser Produced Photons and Particles (CZ.02.1.01/0.0/0.0/16-019/0000789). This work has also been financially supported by the ELIMED INFN project.

Publisher Copyright:
© Copyright © 2020 Cirrone, Petringa, Catalano, Schillaci, Allegra, Amato, Avolio, Costa, Cuttone, Fajstavr, Gallo, Giuffrida, Guarrera, Korn, Larosa, Leanza, Lo Vecchio, Messina, Milluzzo, Olsovcova, Pulvirenti, Pipek, Romano, Rizzo, Russo, Salamone, Scuderi, Velyhan, Vinciguerra, Zakova, Zappalà and Margarone.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

Keywords

dosimetry
ELIMED
laser-driven
laser-driven ions
Monte Carlo
protontherapy

ASJC Scopus subject areas

Biophysics
Materials Science (miscellaneous)
Mathematical Physics
General Physics and Astronomy
Physical and Theoretical Chemistry

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10.3389/fphy.2020.564907Licence: CC BY

ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams
Copyright 2020 the authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 986 KBLicence: CC BY

Cite this

Cirrone, G. A. P., Petringa, G., Catalano, R., Schillaci, F., Allegra, L., Amato, A., Avolio, R., Costa, M., Cuttone, G., Fajstavr, A., Gallo, G., Giuffrida, L., Guarrera, M., Korn, G., Larosa, G., Leanza, R., Lo Vecchio, E., Messina, G., Milluzzo, G., ... Margarone, D. (2020). ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams. Frontiers in Physics, 8, Article 564907. https://doi.org/10.3389/fphy.2020.564907

@article{077c305c256342e3817b3faafd247236,

title = "ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams",

abstract = "The main effort of the laser-driven ion acceleration community is aimed at improving particle beam features (in terms of final maximum energy, particle charge, and beam divergence) and to demonstrate reliable approaches for use for multidisciplinary applications. An ion acceleration target area based on unique laser capabilities is available at ELI-Beamlines (Extreme Light Infrastructure) in the Czech Republic; it is called ELIMAIA (ELI Multidisciplinary Applications of laser-Ion Acceleration) and aims to provide stable and characterized beams of particles accelerated by high-power lasers to offer them to the user community for interdisciplinary studies. The ELIMAIA section dedicated to ion focusing, selection, characterization, and irradiation is named ELIMED (ELI MEDical and multidisciplinary applications). Thanks to ELIMED, very high-dose-rate (around Gy/min) controlled proton and ion beams, with energy levels ranging from 5 to 250 MeV, will be transported to an in-air section dedicated to absolute and relative dosimetry of the laser-generated ions. A transmission dual-gap air ionization chamber will allow an on-line, non-destructive characterization of the ion dose at the user sample irradiation point. The uncertainty in the final dose released onto the sample is expected to be well below 5%. An ELIMED radiobiology pilot experiment is scheduled for 2021, during which in-vitro cell irradiations will be carried out with well-controlled proton beams. In this work, the status of the ELIMED/ELIMAIA beamline will be described along with a complete definition of the main dosimetric systems and of their calibrations carried out at conventional accelerators.",

keywords = "dosimetry, ELIMED, laser-driven, laser-driven ions, Monte Carlo, protontherapy",

author = "Cirrone, {Giuseppe A.P.} and Giada Petringa and Roberto Catalano and Francesco Schillaci and Luciano Allegra and Antonino Amato and Renato Avolio and Michele Costa and Giacomo Cuttone and Antonin Fajstavr and Giuseppe Gallo and Lorenzo Giuffrida and Mariacristina Guarrera and Georg Korn and Giuseppina Larosa and Renata Leanza and {Lo Vecchio}, Enzo and Gustavo Messina and Giuliana Milluzzo and Veronika Olsovcova and Salvatore Pulvirenti and Jan Pipek and Francesco Romano and Daniele Rizzo and Russo, {Antonio D.} and S. Salamone and Valentina Scuderi and Andriy Velyhan and Salvatore Vinciguerra and Martina Zakova and Emilio Zappal{\`a} and Daniele Margarone",

note = "Funding Information: Funding. This work has been supported by the project ELI?Extreme Light Infrastructure?phase 2 (CZ.02.1.01/0.0/0.0/15-008/0000162) from European Regional Development Fund, by the Ministry of Education, Youth and Sports of the Czech Republic (Project No. LQ1606) and by the project Advanced Research Using High Intensity Laser Produced Photons and Particles (CZ.02.1.01/0.0/0.0/16-019/0000789). This work has also been financially supported by the ELIMED INFN project. Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2020 Cirrone, Petringa, Catalano, Schillaci, Allegra, Amato, Avolio, Costa, Cuttone, Fajstavr, Gallo, Giuffrida, Guarrera, Korn, Larosa, Leanza, Lo Vecchio, Messina, Milluzzo, Olsovcova, Pulvirenti, Pipek, Romano, Rizzo, Russo, Salamone, Scuderi, Velyhan, Vinciguerra, Zakova, Zappal{\`a} and Margarone. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",

year = "2020",

month = nov,

day = "13",

doi = "10.3389/fphy.2020.564907",

language = "English",

volume = "8",

journal = "Frontiers in Physics",

publisher = "Frontiers Media S.A.",

}

Cirrone, GAP, Petringa, G, Catalano, R, Schillaci, F, Allegra, L, Amato, A, Avolio, R, Costa, M, Cuttone, G, Fajstavr, A, Gallo, G, Giuffrida, L, Guarrera, M, Korn, G, Larosa, G, Leanza, R, Lo Vecchio, E, Messina, G, Milluzzo, G, Olsovcova, V, Pulvirenti, S, Pipek, J, Romano, F, Rizzo, D, Russo, AD, Salamone, S, Scuderi, V, Velyhan, A, Vinciguerra, S, Zakova, M, Zappalà, E & Margarone, D 2020, 'ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams', Frontiers in Physics, vol. 8, 564907. https://doi.org/10.3389/fphy.2020.564907

TY - JOUR

T1 - ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams

AU - Cirrone, Giuseppe A.P.

AU - Petringa, Giada

AU - Catalano, Roberto

AU - Schillaci, Francesco

AU - Allegra, Luciano

AU - Amato, Antonino

AU - Avolio, Renato

AU - Costa, Michele

AU - Cuttone, Giacomo

AU - Fajstavr, Antonin

AU - Gallo, Giuseppe

AU - Giuffrida, Lorenzo

AU - Guarrera, Mariacristina

AU - Korn, Georg

AU - Larosa, Giuseppina

AU - Leanza, Renata

AU - Lo Vecchio, Enzo

AU - Messina, Gustavo

AU - Milluzzo, Giuliana

AU - Olsovcova, Veronika

AU - Pulvirenti, Salvatore

AU - Pipek, Jan

AU - Romano, Francesco

AU - Rizzo, Daniele

AU - Russo, Antonio D.

AU - Salamone, S.

AU - Scuderi, Valentina

AU - Velyhan, Andriy

AU - Vinciguerra, Salvatore

AU - Zakova, Martina

AU - Zappalà, Emilio

AU - Margarone, Daniele

N1 - Funding Information: Funding. This work has been supported by the project ELI?Extreme Light Infrastructure?phase 2 (CZ.02.1.01/0.0/0.0/15-008/0000162) from European Regional Development Fund, by the Ministry of Education, Youth and Sports of the Czech Republic (Project No. LQ1606) and by the project Advanced Research Using High Intensity Laser Produced Photons and Particles (CZ.02.1.01/0.0/0.0/16-019/0000789). This work has also been financially supported by the ELIMED INFN project. Publisher Copyright: © Copyright © 2020 Cirrone, Petringa, Catalano, Schillaci, Allegra, Amato, Avolio, Costa, Cuttone, Fajstavr, Gallo, Giuffrida, Guarrera, Korn, Larosa, Leanza, Lo Vecchio, Messina, Milluzzo, Olsovcova, Pulvirenti, Pipek, Romano, Rizzo, Russo, Salamone, Scuderi, Velyhan, Vinciguerra, Zakova, Zappalà and Margarone. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/11/13

Y1 - 2020/11/13

N2 - The main effort of the laser-driven ion acceleration community is aimed at improving particle beam features (in terms of final maximum energy, particle charge, and beam divergence) and to demonstrate reliable approaches for use for multidisciplinary applications. An ion acceleration target area based on unique laser capabilities is available at ELI-Beamlines (Extreme Light Infrastructure) in the Czech Republic; it is called ELIMAIA (ELI Multidisciplinary Applications of laser-Ion Acceleration) and aims to provide stable and characterized beams of particles accelerated by high-power lasers to offer them to the user community for interdisciplinary studies. The ELIMAIA section dedicated to ion focusing, selection, characterization, and irradiation is named ELIMED (ELI MEDical and multidisciplinary applications). Thanks to ELIMED, very high-dose-rate (around Gy/min) controlled proton and ion beams, with energy levels ranging from 5 to 250 MeV, will be transported to an in-air section dedicated to absolute and relative dosimetry of the laser-generated ions. A transmission dual-gap air ionization chamber will allow an on-line, non-destructive characterization of the ion dose at the user sample irradiation point. The uncertainty in the final dose released onto the sample is expected to be well below 5%. An ELIMED radiobiology pilot experiment is scheduled for 2021, during which in-vitro cell irradiations will be carried out with well-controlled proton beams. In this work, the status of the ELIMED/ELIMAIA beamline will be described along with a complete definition of the main dosimetric systems and of their calibrations carried out at conventional accelerators.

AB - The main effort of the laser-driven ion acceleration community is aimed at improving particle beam features (in terms of final maximum energy, particle charge, and beam divergence) and to demonstrate reliable approaches for use for multidisciplinary applications. An ion acceleration target area based on unique laser capabilities is available at ELI-Beamlines (Extreme Light Infrastructure) in the Czech Republic; it is called ELIMAIA (ELI Multidisciplinary Applications of laser-Ion Acceleration) and aims to provide stable and characterized beams of particles accelerated by high-power lasers to offer them to the user community for interdisciplinary studies. The ELIMAIA section dedicated to ion focusing, selection, characterization, and irradiation is named ELIMED (ELI MEDical and multidisciplinary applications). Thanks to ELIMED, very high-dose-rate (around Gy/min) controlled proton and ion beams, with energy levels ranging from 5 to 250 MeV, will be transported to an in-air section dedicated to absolute and relative dosimetry of the laser-generated ions. A transmission dual-gap air ionization chamber will allow an on-line, non-destructive characterization of the ion dose at the user sample irradiation point. The uncertainty in the final dose released onto the sample is expected to be well below 5%. An ELIMED radiobiology pilot experiment is scheduled for 2021, during which in-vitro cell irradiations will be carried out with well-controlled proton beams. In this work, the status of the ELIMED/ELIMAIA beamline will be described along with a complete definition of the main dosimetric systems and of their calibrations carried out at conventional accelerators.

KW - dosimetry

KW - ELIMED

KW - laser-driven

KW - laser-driven ions

KW - Monte Carlo

KW - protontherapy

U2 - 10.3389/fphy.2020.564907

DO - 10.3389/fphy.2020.564907

M3 - Article

AN - SCOPUS:85096793995

VL - 8

JO - Frontiers in Physics

JF - Frontiers in Physics

M1 - 564907

ER -

ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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