Enantioselective one-pot synthesis of dihydroquinolones via BINOL-derived Lewis acid catalysis

Peter C. Knipe, Martin D. Smith*

*Corresponding author for this work

Research output: Contribution to journalArticle

8 Citations (Scopus)
67 Downloads (Pure)

Abstract

A high-yielding and diastereoselective route to biologically significant 2-aryl- and 2-alkyl-3-amido dihydroquinolones has been developed in up to 90 : 10 e.r. by employing a novel Lewis acidic BINOL-derived copper(ii) catalyst. 

Original languageEnglish
Pages (from-to)5094-5097
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume12
Issue number28
Early online date13 Jun 2014
DOIs
Publication statusPublished - 2014
Externally publishedYes

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Biochemistry
  • Medicine(all)

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