Enantioselective one-pot synthesis of dihydroquinolones via BINOL-derived Lewis acid catalysis

Peter C. Knipe, Martin D. Smith

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A high-yielding and diastereoselective route to biologically significant 2-aryl- and 2-alkyl-3-amido dihydroquinolones has been developed in up to 90 : 10 e.r. by employing a novel Lewis acidic BINOL-derived copper(ii) catalyst. 

LanguageEnglish
Pages5094-5097
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume12
Issue number28
Early online date13 Jun 2014
DOIs
Publication statusPublished - 2014
Externally publishedYes

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Lewis Acids
Catalysis
catalysis
Copper
routes
catalysts
copper
acids
Catalysts
synthesis
naphthol BINOL

Cite this

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abstract = "A high-yielding and diastereoselective route to biologically significant 2-aryl- and 2-alkyl-3-amido dihydroquinolones has been developed in up to 90 : 10 e.r. by employing a novel Lewis acidic BINOL-derived copper(ii) catalyst. ",
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Enantioselective one-pot synthesis of dihydroquinolones via BINOL-derived Lewis acid catalysis. / Knipe, Peter C.; Smith, Martin D.

In: Organic and Biomolecular Chemistry, Vol. 12, No. 28, 2014, p. 5094-5097.

Research output: Contribution to journalArticle

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