Epstein–Barr virus positive inflammatory pseudo-tumour of the spleen: A case report and literature review

P Loughlin*, A. Brady, E Devlin, D. T. McManus, R.A. J. Spence

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)
13 Downloads (Pure)

Abstract

INTRODUCTION: Epstein-Barr virus positive inflammatory pseudo-tumour (IPT) of the spleen is an uncommon, frequently asymptomatic entity, which is typically picked up as an incidental finding on imaging.

PRESENTATION OF CASE: We present a case of EBV positive IPT of the spleen which presented as an incidental finding on CT in a patient with a history of malignancy. Splenectomy was performed.

DISCUSSION: IPTs are benign spindle cell lesions of varying aetiology, which can arise in a variety of tissues, including the spleen. In situ hybridisation showed strong staining for Epstein-Barr virus RNA in our case, in common with many similar lesions described in the literature. The differential diagnosis of such spindle cell tumours is discussed.

CONCLUSION: Radiologically, EBV positive spindle cell tumours are indistinguishable from malignant lesions such as lymphoma and diagnosis is made on histology, usually at splenectomy.

Original languageEnglish
Pages (from-to)186-188
Number of pages3
JournalInternational Journal of Surgery Case Reports
Volume5
Issue number4
DOIs
Publication statusPublished - 14 Feb 2014
Externally publishedYes

Bibliographical note

Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

Fingerprint

Dive into the research topics of 'Epstein–Barr virus positive inflammatory pseudo-tumour of the spleen: A case report and literature review'. Together they form a unique fingerprint.

Cite this