Essential oils for clinical aromatherapy: a comprehensive review

Lalitkumar K. Vora*, Amol D. Gholap, Navnath T. Hatvate, Padmashri Naren, Sabiya Khan, Vivek P. Chavda*, Pankti C. Balar, Jimil Gandhi, Dharmendra Kumar Khatri*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Ethnopharmacological relevance
Aromatherapy, a holistic healing practice utilizing the aromatic essences of plant-derived essential oils, has gained significant attention for its therapeutic potential in promoting overall well-being. Use of phytoconstituent based essential oil has played a significant role in the evolving therapeutic avenue of aromatherapy as a complementary system of medicine.

Aim of the study: This comprehensive review article aims to explore the usage of essential oils for aromatherapy, shedding light on their diverse applications, scientific evidence, and safety considerations. Furthermore, the growing interest in using essential oils as complementary therapies in conjunction with conventional medicine is explored, underscoring the significance of collaborative healthcare approaches.

Materials and methods
Literature search was performed from databases like PubMed, ScienceDirect, Scopus, and Bentham using keywords like Aromatherapy, Aromatic Plants, Essential oils, Phytotherapy, and complementary medicine. The keywords were used to identify literature with therapeutic and mechanistic details of herbal agents with desired action.

The integration of traditional knowledge with modern scientific research has led to a renewed interest in essential oils as valuable tools in contemporary healthcare. Various extraction methods used to obtain essential oils are presented, emphasizing their impact on the oil's chemical composition and therapeutic properties. Additionally, the article scrutinizes the factors influencing the quality and purity of essential oils, elucidating the significance of standardization and certification for safe usage. A comprehensive assessment of the therapeutic effects of essential oils is provided, encompassing their potential as antimicrobial, analgesic, anxiolytic, and anti-inflammatory agents, among others. Clinical trials and preclinical studies are discussed to consolidate the existing evidence on their efficacy in treating diverse health conditions, both physical and psychological. Safety considerations are of paramount importance when employing essential oils, and this review addresses potential adverse effects, contraindications, and best practices to ensure responsible usage.

This comprehensive review provides valuable insights into the exploration of essential oils for aromatherapy, emphasizing their potential as natural and potent remedies for a wide range of ailments. By amalgamating traditional wisdom and modern research, this article aims to encourage further investigation into the therapeutic benefits of essential oils while advocating for their responsible and evidence-based incorporation into healthcare practices.

Original languageEnglish
Article number118180
Number of pages21
JournalJournal of Ethnopharmacology
Early online date17 Apr 2024
Publication statusEarly online date - 17 Apr 2024


  • Aromatherapy
  • Aromatherapy mechanism
  • Essential oils
  • Mood disorders
  • Phytotherapy
  • Sleep disorders

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery


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