Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)

A. Osorio, R.L. Milne, G. Pita, P. Peterlongo, T. Heikkinen, J. Simard, G. Chenevix-Trench, A.B. Spurdle, J. Beesley, X. Chen, S. Healey, S.L. Neuhausen, Y.C. Ding, F.J. Couch, X. Wang, N. Lindor, S. Manoukian, M. Barile, A. Viel, L. TizzoniC.I. Szabo, L. Foretova, M. Zikan, K. Claes, M.H. Greene, P. Mai, G. Rennert, F. Lejbkowicz, O. Barnett-Griness, I.L. Andrulis, H. Ozcelik, N. Weerasooriya, A.M. Gerdes, M. Thomassen, D.G. Cruger, M.A. Caligo, E. Friedman, B. Kaufman, Y. Laitman, S. Cohen, T. Kontorovich, R. Gershoni-Baruch, E. Dagan, H. Jernstrom, M.S. Askmalm, B. Arver, B. Malmer, S.M. Domchek, K.L. Nathanson, J. Brunet, T.R.Y. Cajal, D. Yannoukakos, U. Hamann, F.B.L. Hogervorst, S. Verhoef, E.B.G. Garcia, J.T. Wijnen, A. Van Den Ouweland, D.F. Easton, S. Peock, M. Cook, C.T. Oliver, D. Frost, C. Luccarini, D.G. Evans, F. Lalloo, R. Eeles, G. Pichert, J. Cook, S. Hodgson, Patrick Morrison, F. Douglas, A.K. Godwin, O.M. Sinilnikova, L. Barjhoux, D. Stoppa-Lyonnet, V. Moncoutier, S. Giraud, C. Cassini, L. Olivier-Faivre, F. Revillion, J.P. Peyrat, D. Muller, J.P. Fricker, H.T. Lynch, E.M. John, S. Buys, M. Daly, J.L. Hopper, M.B. Terry, A. Miron, Y. Yassin, D. Goldgar, C.F. Singer, D. Gschwantler-Kaulich, G. Pfeiler, A.C. Spiess, T.V. Hansen, O.T. Johannsson, T. Kirchhoff, K. Offit, K. Kosarin, M. Piedmonte, G.C. Rodriguez, K. Wakeley, J.F. Boggess, J. Basil, P.E. Schwartz, S.V. Blank, A.E. Toland, M. Montagna, C. Casella, E.N. Imyanitov, A. Allavena, R.K. Schmutzler, B. Versmold, C. Engel, A. Meindl, N. Ditsch, N. Arnold, D. Niederacher, H. Deissler, B. Fiebig, R. Varon-Mateeva, D. Schaefer, U.G. Froster, T. Caldes, M. De La Hoya, L. McGuffog, A.C. Antoniou, H. Nevanlinna, P. Radice, J. Benitez

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

BACKGROUND: In this study we aimed to evaluate the role of a SNP in intron I of the ERCC4 gene (rs744154), previously reported to be associated with a reduced risk of breast cancer in the general population, as a breast cancer risk modifier in BRCA1 and BRCA2 mutation carriers.
Original languageEnglish
Pages (from-to)2048-2054
Number of pages7
JournalBritish Journal of Cancer
Volume101
Issue number12
DOIs
Publication statusPublished - Dec 2009

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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