Abstract
Protection against Fasciola hepatica in goats immunized with Peroxiredoxin (Prx) was assessed. The experimental trial consisted of three groups of seven animals: group 1 were unimmunized and uninfected, group 2 were immunized with adjuvant only and group 3 were immunized with recombinant Prx in adjuvant (immunized and infected). Immunization with Prx in Quil A adjuvant, group 3, induced a reduction in fluke burden of 33.04% when compared to adjuvant control, group 2, although this difference was not significant. The hepatic gross and microscopical morphometric study revealed lower damage in the Prx-immunized compared to group 2 (p
Original language | English |
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Pages (from-to) | 2832-2840 |
Number of pages | 9 |
Journal | Vaccine |
Volume | 28 |
Issue number | 16 |
DOIs | |
Publication status | Published - 01 Apr 2010 |
ASJC Scopus subject areas
- Molecular Medicine
- General Immunology and Microbiology
- Infectious Diseases
- Public Health, Environmental and Occupational Health
- General Veterinary