Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families

K S Kendler, C J MacLean, F A O'Neill, J Burke, B Murphy, F Duke, R Shinkwin, S M Easter, B T Webb, J Zhang, D Walsh, R E Straub

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172 Citations (Scopus)

Abstract

This study was an attempt to replicate evidence for a vulnerability locus for schizophrenia and associated disorders in the 8p22-21 region reported by Pulver and colleagues.
Original languageEnglish
Pages (from-to)1534-40
Number of pages7
JournalAmerican Journal of Psychiatry
Volume153
Issue number12
Publication statusPublished - Dec 1996

Keywords

  • Chromosomes, Human, Pair 8
  • Family
  • Female
  • Genetic Heterogeneity
  • Genetic Linkage
  • Genetic Markers
  • Humans
  • Ireland
  • Lod Score
  • Male
  • Models, Genetic
  • Pedigree
  • Schizophrenia

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  • Cite this

    Kendler, K. S., MacLean, C. J., O'Neill, F. A., Burke, J., Murphy, B., Duke, F., Shinkwin, R., Easter, S. M., Webb, B. T., Zhang, J., Walsh, D., & Straub, R. E. (1996). Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families. American Journal of Psychiatry, 153(12), 1534-40.