Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease

Jaume Pons; Jaume Sauleda; Verónica Regueiro; Carmen Santos; Meritxell López; Joana Ferrer; Alvar G N Agustí; José A Bengoechea

doi:10.1186/1465-9921-7-64

Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease

Jaume Pons, Jaume Sauleda, Verónica Regueiro, Carmen Santos, Meritxell López, Joana Ferrer, Alvar G N Agustí, José A Bengoechea

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

74 Citations (Scopus)

Abstract

Chronic obstructive pulmonary disease (COPD) is characterised by pulmonary and systemic inflammation which flare-up during episodes of acute exacerbation (AECOPD). Given the role of Toll-like receptors (TLRs) in the induction of inflammatory responses we investigated the involvement of TLRs in COPD pathogenesis.

Original language	English
Pages (from-to)	64
Journal	Respiratory Research
Volume	7
DOIs	https://doi.org/10.1186/1465-9921-7-64
Publication status	Published - 2006

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title = "Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease",

abstract = "Chronic obstructive pulmonary disease (COPD) is characterised by pulmonary and systemic inflammation which flare-up during episodes of acute exacerbation (AECOPD). Given the role of Toll-like receptors (TLRs) in the induction of inflammatory responses we investigated the involvement of TLRs in COPD pathogenesis.",

author = "Jaume Pons and Jaume Sauleda and Ver{\'o}nica Regueiro and Carmen Santos and Meritxell L{\'o}pez and Joana Ferrer and Agust{\'i}, {Alvar G N} and Bengoechea, {Jos{\'e} A}",

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T1 - Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease

AU - Pons, Jaume

AU - Sauleda, Jaume

AU - Regueiro, Verónica

AU - Santos, Carmen

AU - López, Meritxell

AU - Ferrer, Joana

AU - Agustí, Alvar G N

AU - Bengoechea, José A

PY - 2006

Y1 - 2006

N2 - Chronic obstructive pulmonary disease (COPD) is characterised by pulmonary and systemic inflammation which flare-up during episodes of acute exacerbation (AECOPD). Given the role of Toll-like receptors (TLRs) in the induction of inflammatory responses we investigated the involvement of TLRs in COPD pathogenesis.

AB - Chronic obstructive pulmonary disease (COPD) is characterised by pulmonary and systemic inflammation which flare-up during episodes of acute exacerbation (AECOPD). Given the role of Toll-like receptors (TLRs) in the induction of inflammatory responses we investigated the involvement of TLRs in COPD pathogenesis.

U2 - 10.1186/1465-9921-7-64

DO - 10.1186/1465-9921-7-64

M3 - Article

C2 - 16606450

VL - 7

SP - 64

JO - Respiratory Research

JF - Respiratory Research

ER -

Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease

Abstract

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