Facile synthesis of methyl 2-amino-3-(2-methyl-3-quinolyl)propanoate

M Hadden; PJ Stevenson

Facile synthesis of methyl 2-amino-3-(2-methyl-3-quinolyl)propanoate

M Hadden, PJ Stevenson^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Methyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2-carboxylate 5, readily available in one step by a 1,3-dipolar cycloaddition, undergoes reduction, cyclisation and fragmentation to the corresponding quinoline when treated with hydrogen and palladium.

Original language	English
Pages (from-to)	796-797
Number of pages	3
Journal	Journal of Chemical Research
Issue number	12
Publication status	Published - Dec 1998

Keywords

1,3-DIPOLAR CYCLOADDITION
ACID

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@article{99e238d2f81e45b3be65d793e42eb4c3,

title = "Facile synthesis of methyl 2-amino-3-(2-methyl-3-quinolyl)propanoate",

abstract = "Methyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2-carboxylate 5, readily available in one step by a 1,3-dipolar cycloaddition, undergoes reduction, cyclisation and fragmentation to the corresponding quinoline when treated with hydrogen and palladium.",

keywords = "1,3-DIPOLAR CYCLOADDITION, ACID",

author = "M Hadden and PJ Stevenson",

year = "1998",

month = dec,

language = "English",

pages = "796--797",

journal = "Journal of Chemical Research",

issn = "0308-2342",

publisher = "Science Reviews Ltd",

number = "12",

}

TY - JOUR

T1 - Facile synthesis of methyl 2-amino-3-(2-methyl-3-quinolyl)propanoate

AU - Hadden, M

AU - Stevenson, PJ

PY - 1998/12

Y1 - 1998/12

N2 - Methyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2-carboxylate 5, readily available in one step by a 1,3-dipolar cycloaddition, undergoes reduction, cyclisation and fragmentation to the corresponding quinoline when treated with hydrogen and palladium.

AB - Methyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2-carboxylate 5, readily available in one step by a 1,3-dipolar cycloaddition, undergoes reduction, cyclisation and fragmentation to the corresponding quinoline when treated with hydrogen and palladium.

KW - 1,3-DIPOLAR CYCLOADDITION

KW - ACID

M3 - Article

SP - 796

EP - 797

JO - Journal of Chemical Research

JF - Journal of Chemical Research

SN - 0308-2342

IS - 12

ER -

Facile synthesis of methyl 2-amino-3-(2-methyl-3-quinolyl)propanoate

Abstract

Keywords

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