Facile synthesis of methyl 2-amino-3-(2-methyl-3-quinolyl)propanoate

M Hadden, PJ Stevenson*

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Methyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2-carboxylate 5, readily available in one step by a 1,3-dipolar cycloaddition, undergoes reduction, cyclisation and fragmentation to the corresponding quinoline when treated with hydrogen and palladium.

Original languageEnglish
Pages (from-to)796-797
Number of pages3
JournalJournal of Chemical Research
Issue number12
Publication statusPublished - Dec 1998

Keywords

  • 1,3-DIPOLAR CYCLOADDITION
  • ACID

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