Methyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2-carboxylate 5, readily available in one step by a 1,3-dipolar cycloaddition, undergoes reduction, cyclisation and fragmentation to the corresponding quinoline when treated with hydrogen and palladium.
|Number of pages||3|
|Journal||Journal of Chemical Research|
|Publication status||Published - Dec 1998|
- 1,3-DIPOLAR CYCLOADDITION