Abstract
Solid-phase oligonucleotide conjugation by nitrile oxide-alkyne click cycloaddition chemistry has been successfully demonstrated; the reaction, compatible with all nucleobases, requires no metal catalyst and proceeds under physiological conditions.
Original language | English |
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Pages (from-to) | 3276-3278 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 22 |
Issue number | 22 |
Early online date | 22 Apr 2009 |
DOIs | |
Publication status | Published - 2009 |
ASJC Scopus subject areas
- Catalysis
- General Chemistry
- Ceramics and Composites
- Electronic, Optical and Magnetic Materials
- Materials Chemistry
- Metals and Alloys
- Surfaces, Coatings and Films