Abstract
The ultra short duration of laser-driven multi-MeV ion bursts offers the possibility of radiobiological studies at extremely high dose rates. Employing the TARANIS Terawatt laser at Queen's University, the effect of proton irradiation at MeV-range energies on live cells has been investigated at dose rates exceeding 10 Gy/s as a single exposure. A clonogenic assay showed consistent lethal effects on V-79 live, cells, which, even at these dose rates, appear to be in line with previously published results employing conventional sources. A Relative Biological Effectiveness (RBE) of 1.4±0.2 at 10% survival is estimated from a comparison with a 225 kVp X-ray source.
Original language | English |
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Title of host publication | AIP Conference Proceedings |
Pages | 87-89 |
Number of pages | 3 |
Volume | 1546 |
Edition | 1 |
DOIs | |
Publication status | Published - 2013 |
Event | AIP Conference 2012 - Catania, Italy Duration: 18 Oct 2012 → 19 Oct 2012 |
Conference
Conference | AIP Conference 2012 |
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Country/Territory | Italy |
City | Catania |
Period | 18/10/2012 → 19/10/2012 |