The ultra short duration of laser-driven multi-MeV ion bursts offers the possibility of radiobiological studies at extremely high dose rates. Employing the TARANIS Terawatt laser at Queen's University, the effect of proton irradiation at MeV-range energies on live cells has been investigated at dose rates exceeding 10 Gy/s as a single exposure. A clonogenic assay showed consistent lethal effects on V-79 live, cells, which, even at these dose rates, appear to be in line with previously published results employing conventional sources. A Relative Biological Effectiveness (RBE) of 1.4±0.2 at 10% survival is estimated from a comparison with a 225 kVp X-ray source.
|Title of host publication||AIP Conference Proceedings|
|Number of pages||3|
|Publication status||Published - 2013|
|Event||AIP Conference 2012 - Catania, Italy|
Duration: 18 Oct 2012 → 19 Oct 2012
|Conference||AIP Conference 2012|
|Period||18/10/2012 → 19/10/2012|