Flux limitation mechanisms arising in multiscale modelling of cancer invasion

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Abstract

Tumour invasion is an essential stage of cancer progression. Its main drivers are diffusion and taxis, a directed movement along the gradient of a stimulus. Here we review models with flux limited diffusion and/or taxis which have applications in modelling of cell migration, particularly in cancer. Flux limitation ensures control upon propagation speeds, precluding unnaturally quick spread which is typical for traditional parabolic equations. We recall the main properties of models with flux limitation effects and discuss ways to construct them, concentrating on multiscale derivations from kinetic transport equations.
Original languageEnglish
Pages (from-to)5-26
JournalMathematical Proceedings of the Royal Irish Academy
Volume122A
Issue number1
DOIs
Publication statusPublished - 30 Mar 2022

Bibliographical note

Review article

Keywords

  • math.AP
  • 35K55 35K65 35Q49 35Q83 35Q92 45K05 92C17

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