Abstract
Aim of this study was to examine secular trends in the incidence of type 1 diabetes in children aged 0–14 years in Hungary over the period 1989–2009.
Methods: Newly diagnosed children with type 1 diabetes aged 0–14 years in Hungary were prospectively registered from 1989 to 2009. Standardized incidence rates were calculated and secular trends were estimated using Poisson regression analysis.
Results: Between 1989 and 2009 a total number of 3432children were identified, giving a standardized incidence rate of 12.5 (95%CI 12.1–12.9) per 100 000 person/year. The overall incidence rate has doubled from 7.7 (95%CI 6.4-9.15) per 100 000 per year in 1989 to 18.2 (95%CI15.7–20.9) per 100 000 per year in 2009. A significant linear trend in incidence (p<0.001) has been observed overtime, with a mean annual increase of 4.4%. The increase in incidence was present in both genders and in all age groups, with the largest relative increase in the youngest age group (6.2%; p<0.001).
Conclusion: The incidence of type 1 diabetes in Hungarian children continues to increase, with the highest rate in the very young.
Methods: Newly diagnosed children with type 1 diabetes aged 0–14 years in Hungary were prospectively registered from 1989 to 2009. Standardized incidence rates were calculated and secular trends were estimated using Poisson regression analysis.
Results: Between 1989 and 2009 a total number of 3432children were identified, giving a standardized incidence rate of 12.5 (95%CI 12.1–12.9) per 100 000 person/year. The overall incidence rate has doubled from 7.7 (95%CI 6.4-9.15) per 100 000 per year in 1989 to 18.2 (95%CI15.7–20.9) per 100 000 per year in 2009. A significant linear trend in incidence (p<0.001) has been observed overtime, with a mean annual increase of 4.4%. The increase in incidence was present in both genders and in all age groups, with the largest relative increase in the youngest age group (6.2%; p<0.001).
Conclusion: The incidence of type 1 diabetes in Hungarian children continues to increase, with the highest rate in the very young.
| Translated title of the contribution | Always up or peaks and highlands? Incidence of childhood type 1 diabetes in Hungary 1989-2009 |
|---|---|
| Original language | Other |
| Pages (from-to) | 1692-1697 |
| Journal | Orvosi Hetilap |
| Volume | 152 |
| Issue number | 42 |
| DOIs | |
| Publication status | Published - 01 Oct 2011 |
ASJC Scopus subject areas
- General Medicine
