Four-dimensional CT analysis of vocal cords mobility for highly focused single vocal cord irradiation

S. O S Osman*, H. C J de Boer, B. J M Heijmen, Peter C. Levendag

*Corresponding author for this work

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background and Purpose: To quantify respiratory motion of the vocal cords during normal respiration using 4D-CT. The final goal is to develop a technique for single vocal cord irradiation (SVCI) in early glottic carcinoma. Sparing the non-involved cord and surrounding structures has the potential to preserve voice quality and allow re-irradiation of recurrent and second primary tumors. Material and methods: Four-dimensional CTs of 1 mm slice thickness from 10 early glottic carcinoma patients were acquired. The lateral dimensions of the air gap separating the vocal cords were measured anteriorly, at mid-level and posteriorly at each phase of the 4D-CTs. The corresponding anterior-posterior gaps were similarly measured. Cranio-caudal vocal cords movements during breathing were derived from the shifts of the arythenoids. Results: The population-averaged mean gap size ± the corresponding standard deviation due to breathing (SDB) for the lateral gaps was 5.8 ± 0.7 mm anteriorly, 8.7 ± 0.9 mm at mid-level, and 11.0 ± 1.3 mm posteriorly. Anterior-posterior gap values were 21.7 ± 0.7 mm, while cranio-caudal shift SDB was 0.8 mm. Conclusion: Vocal cords breathing motions were found to be small relative to their separation. Hence, breathing motion does not seem to be a limiting factor for SVCI.

Original languageEnglish
Pages (from-to)19-27
Number of pages9
JournalRadiotherapy and Oncology
Volume89
Issue number1
DOIs
Publication statusPublished - 01 Oct 2008

Fingerprint

Four-Dimensional Computed Tomography
Vocal Cords
Respiration
Tongue
Voice Quality
Carcinoma
Air
Population

Keywords

  • 4D-CT
  • Early glottic carcinoma
  • IGRT
  • Vocal cords
  • Voice quality

Cite this

Osman, S. O S ; de Boer, H. C J ; Heijmen, B. J M ; Levendag, Peter C. / Four-dimensional CT analysis of vocal cords mobility for highly focused single vocal cord irradiation. In: Radiotherapy and Oncology. 2008 ; Vol. 89, No. 1. pp. 19-27.
@article{0b14f0cf25504febbc256857868c085e,
title = "Four-dimensional CT analysis of vocal cords mobility for highly focused single vocal cord irradiation",
abstract = "Background and Purpose: To quantify respiratory motion of the vocal cords during normal respiration using 4D-CT. The final goal is to develop a technique for single vocal cord irradiation (SVCI) in early glottic carcinoma. Sparing the non-involved cord and surrounding structures has the potential to preserve voice quality and allow re-irradiation of recurrent and second primary tumors. Material and methods: Four-dimensional CTs of 1 mm slice thickness from 10 early glottic carcinoma patients were acquired. The lateral dimensions of the air gap separating the vocal cords were measured anteriorly, at mid-level and posteriorly at each phase of the 4D-CTs. The corresponding anterior-posterior gaps were similarly measured. Cranio-caudal vocal cords movements during breathing were derived from the shifts of the arythenoids. Results: The population-averaged mean gap size ± the corresponding standard deviation due to breathing (SDB) for the lateral gaps was 5.8 ± 0.7 mm anteriorly, 8.7 ± 0.9 mm at mid-level, and 11.0 ± 1.3 mm posteriorly. Anterior-posterior gap values were 21.7 ± 0.7 mm, while cranio-caudal shift SDB was 0.8 mm. Conclusion: Vocal cords breathing motions were found to be small relative to their separation. Hence, breathing motion does not seem to be a limiting factor for SVCI.",
keywords = "4D-CT, Early glottic carcinoma, IGRT, Vocal cords, Voice quality",
author = "Osman, {S. O S} and {de Boer}, {H. C J} and Heijmen, {B. J M} and Levendag, {Peter C.}",
year = "2008",
month = "10",
day = "1",
doi = "10.1016/j.radonc.2008.05.016",
language = "English",
volume = "89",
pages = "19--27",
journal = "Radiotherapy and Oncology",
issn = "0167-8140",
publisher = "Elsevier",
number = "1",

}

Four-dimensional CT analysis of vocal cords mobility for highly focused single vocal cord irradiation. / Osman, S. O S; de Boer, H. C J; Heijmen, B. J M; Levendag, Peter C.

In: Radiotherapy and Oncology, Vol. 89, No. 1, 01.10.2008, p. 19-27.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Four-dimensional CT analysis of vocal cords mobility for highly focused single vocal cord irradiation

AU - Osman, S. O S

AU - de Boer, H. C J

AU - Heijmen, B. J M

AU - Levendag, Peter C.

PY - 2008/10/1

Y1 - 2008/10/1

N2 - Background and Purpose: To quantify respiratory motion of the vocal cords during normal respiration using 4D-CT. The final goal is to develop a technique for single vocal cord irradiation (SVCI) in early glottic carcinoma. Sparing the non-involved cord and surrounding structures has the potential to preserve voice quality and allow re-irradiation of recurrent and second primary tumors. Material and methods: Four-dimensional CTs of 1 mm slice thickness from 10 early glottic carcinoma patients were acquired. The lateral dimensions of the air gap separating the vocal cords were measured anteriorly, at mid-level and posteriorly at each phase of the 4D-CTs. The corresponding anterior-posterior gaps were similarly measured. Cranio-caudal vocal cords movements during breathing were derived from the shifts of the arythenoids. Results: The population-averaged mean gap size ± the corresponding standard deviation due to breathing (SDB) for the lateral gaps was 5.8 ± 0.7 mm anteriorly, 8.7 ± 0.9 mm at mid-level, and 11.0 ± 1.3 mm posteriorly. Anterior-posterior gap values were 21.7 ± 0.7 mm, while cranio-caudal shift SDB was 0.8 mm. Conclusion: Vocal cords breathing motions were found to be small relative to their separation. Hence, breathing motion does not seem to be a limiting factor for SVCI.

AB - Background and Purpose: To quantify respiratory motion of the vocal cords during normal respiration using 4D-CT. The final goal is to develop a technique for single vocal cord irradiation (SVCI) in early glottic carcinoma. Sparing the non-involved cord and surrounding structures has the potential to preserve voice quality and allow re-irradiation of recurrent and second primary tumors. Material and methods: Four-dimensional CTs of 1 mm slice thickness from 10 early glottic carcinoma patients were acquired. The lateral dimensions of the air gap separating the vocal cords were measured anteriorly, at mid-level and posteriorly at each phase of the 4D-CTs. The corresponding anterior-posterior gaps were similarly measured. Cranio-caudal vocal cords movements during breathing were derived from the shifts of the arythenoids. Results: The population-averaged mean gap size ± the corresponding standard deviation due to breathing (SDB) for the lateral gaps was 5.8 ± 0.7 mm anteriorly, 8.7 ± 0.9 mm at mid-level, and 11.0 ± 1.3 mm posteriorly. Anterior-posterior gap values were 21.7 ± 0.7 mm, while cranio-caudal shift SDB was 0.8 mm. Conclusion: Vocal cords breathing motions were found to be small relative to their separation. Hence, breathing motion does not seem to be a limiting factor for SVCI.

KW - 4D-CT

KW - Early glottic carcinoma

KW - IGRT

KW - Vocal cords

KW - Voice quality

UR - http://www.scopus.com/inward/record.url?scp=54849189900&partnerID=8YFLogxK

U2 - 10.1016/j.radonc.2008.05.016

DO - 10.1016/j.radonc.2008.05.016

M3 - Article

C2 - 18556079

AN - SCOPUS:54849189900

VL - 89

SP - 19

EP - 27

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

SN - 0167-8140

IS - 1

ER -